Knockout

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1
PPAR gamma is required for the differentiation of adipose tissue in vivo and in vitro
Rosen ED;Sarraf P;Troy AE;Bradwin G;Moore K;Milstone DS;Spiegelman BM;Mortensen RM;;
1999 molecular cell 408 views
2
C/EBPbeta, when expressed from the C/ebpalpha gene locus, can functionally replace C/EBPalpha in liver but not in adipose tissue
Chen SS;Chen JF;Johnson PF;Muppala V;Lee YH;;
2000 molecular and cellular biology 482 views
3
Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage
Kim SU;Jin MH;Kim YS;Lee SH;Cho YS;Cho KJ;Lee KS;Kim YI;Kim GW;Kim JM;Lee TH;Lee YH;Shong M;Kim HC;C...
2011 neurobiology of aging 344 views
5
Peroxiredoxin I deficiency increases LPS‑induced lethal shock in mice
Sun HN;Feng L;Wang AG;Wang JY;Liu L;Jin MH;Shen GN;Jin CH;Lee DS;Kwon TH;Cui YD;Yu DY;Han YH;;
2018 molecular medicine reports 370 views
6
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
Kubota N;Terauchi Y;Miki H;Tamemoto H;Yamauchi T;Komeda K;Satoh S;Nakano R;Ishii C;Sugiyama T;Eto K;...
1999 molecular cell 440 views
7
GIT1 contributes to autophagy in osteoclast through disruption of the binding of Beclin1 and Bcl2 under starvation condition
Zhao SJ;Kong FQ;Cai W;Xu T;Zhou ZM;Wang ZB;Xu AD;Yang YQ;Chen J;Tang PY;Wang Q;Cheng L;Luo YJ;Zhou Z...
2018 Cell death & disease 294 views
8
PPAR gamma is required for placental, cardiac, and adipose tissue development
Barak Y;Nelson MC;Ong ES;Jones YZ;Ruiz-Lozano P;Chien KR;Koder A;Evans RM;;
1999 molecular cell 335 views
9
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
Hayhurst GP;Lee YH;Lambert G;Ward JM;Gonzalez FJ;;
2001 molecular and cellular biology 377 views
10
Cross-regulation of C/EBP alpha and PPAR gamma controls the transcriptional pathway of adipogenesis and insulin sensitivity
Wu Z;Rosen ED;Brun R;Hauser S;Adelmant G;Troy AE;McKeon C;Darlington GJ;Spiegelman BM;;
1999 molecular cell 339 views
11
Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome
Caldwell ASL;Edwards MC;Desai R;Jimenez M;Gilchrist RB;Handelsman DJ;Walters KA;;
2017 Proceedings of the National Academy of Sciences of... 335 views
12
Etoposide selectively ablates activated T cells to control the immunoregulatory disorder hemophagocytic lymphohistiocytosis
Johnson TS;Terrell CE;Millen SH;Katz JD;Hildeman DA;Jordan MB;;
2014 journal of immunology (baltimore, md : 1950) 308 views
13
A Saccharomyces cerevisiae mutant with increased virulence
Wheeler RT;Kupiec M;Magnelli P;Abeijon C;Fink GR;;
2003 Proceedings of the National Academy of Sciences of... 316 views
14
Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
Jacobs JJ;Scheijen B;Voncken JW;Kieboom K;Berns A;van Lohuizen M;;
1999 genes & development 254 views
15
Prostate tumor progression is mediated by a paracrine TGF-beta/Wnt3a signaling axis
Li X;Placencio V;Iturregui JM;Uwamariya C;Sharif-Afshar AR;Koyama T;Hayward SW;Bhowmick NA;;
2008 Oncogene 300 views
17
Disruption of the ARF-Mdm2-p53 tumor suppressor pathway in Myc-induced lymphomagenesis
Eischen CM;Weber JD;Roussel MF;Sherr CJ;Cleveland JL;;
1999 genes & development 269 views
18
Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-β/Smad signalling
Romero D;Kawano Y;Bengoa N;Walker MM;Maltry N;Niehrs C;Waxman J;Kypta R;;
2013 journal of cell science 249 views
19
Noggin is a mesenchymally derived stimulator of hair-follicle induction
Botchkarev VA;Botchkareva NV;Roth W;Nakamura M;Chen LH;Herzog W;Lindner G;McMahon JA;Peters C;Lauste...
1999 Nature Cell Biology 248 views
20
Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis
Könner AC;Hess S;Tovar S;Mesaros A;Sánchez-Lasheras C;Evers N;Verhagen LA;Brönneke HS;Kleinridders A...
2011 cell metabolism 344 views

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