Peroxiredoxin I deficiency increases LPS‑induced lethal shock in mice

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ID: 113522
2018
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Abstract
Peroxiredoxin I (Prx I) plays a role in regulating macrophage proinflammatory cytokine production and gene expression and participates in immune regulation. However, the possible protective role of Prx I in endotoxin‑induced lethal shock is poorly understood. In the present study, western blot analy …
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Authors Sun HN;Feng L;Wang AG;Wang JY;Liu L;Jin MH;Shen GN;Jin CH;Lee DS;Kwon TH;Cui YD;Yu DY;Han YH;;
Journal molecular medicine reports
Year 2018
DOI
DOI not found
URL
https://www.pubmed.gov/29901182/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine Liver / pathology Knockout liver / drug effects hu-nan sun peroxiredoxins / genetics* shock pmid:29901182 doi:10.3892/mmr.2018.9170 li feng ying-hao han apoptosis / genetics caspase 3 / genetics gene expression regulation / genetics interleukin-10 / blood lipopolysaccharides / toxicity macrophages / metabolism macrophages / pathology oxidative stress / genetics* septic / blood septic / chemically induced septic / genetics*

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