Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage

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ID: 111842
2011
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Abstract
Reactive oxygen species (ROS), routinely produced in biological reactions, contribute to both normal aging and age-related decline in cognitive function. However, little is known regarding the involvement of specific antioxidants in the underlying mechanism(s). Here, we examined if peroxiredoxin II …
Reference Key
su2011neurobiologyperoxiredoxin Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Kim SU, Jin MH, Kim YS, Lee SH, Cho YS, Cho KJ, Lee KS, Kim YI, Kim GW, Kim JM, Lee TH, Lee YH, Shong M, Kim HC, Chang KT, Yu DY, Lee DS
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Journal neurobiology of aging
Year 2011
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/19577336
Keywords
Administration National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine behavior research support non-u.s. gov't male Animal Knockout microscopy electron pmid:19577336 doi:10.1016/j.neurobiolaging.2009.05.017 sun-uk kim mei-hua jin dong-seok lee oral aging / physiology* antioxidants / administration & dosage creb-binding protein / genetics creb-binding protein / metabolism cognition / drug effects cognition / physiology* cyclic amp-dependent protein kinases / metabolism enzyme activation / drug effects enzyme activation / genetics extracellular signal-regulated map kinases / metabolism hippocampus / cytology* learning disabilities / diet therapy learning disabilities / genetics long-term potentiation / drug effects long-term potentiation / genetics malondialdehyde / metabolism maze learning / physiology transmission / methods mitochondria / pathology neurons / drug effects neurons / metabolism neurons / physiology* neurons / ultrastructure peroxiredoxins / deficiency peroxiredoxins / metabolism* protein carbonylation / drug effects reactive oxygen species vitamin e / administration & dosage

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