Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis

Clicks: 403
ID: 268636
2000
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #8 of 22 articles by views in Infection and immunity

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
In experimental visceral leishmaniasis, in which the tissue macrophage is the target, in vivo responsiveness to conventional chemotherapy (pentavalent antimony [Sb]) requires a T-cell-dependent mechanism. To determine if this mechanism involves gamma interferon (IFN-gamma)-induced activation and/or …
Reference Key
hw2000infectionroles Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Murray HW;Delph-Etienne S;;
Journal Infection and immunity
Year 2000
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/10603400
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't female male Disease Models Animal P.H.S. Liver / pathology Knockout interferon-gamma / genetics enzyme inhibitors / pharmacology chronic / immunology amphotericin b / therapeutic use Chronic / genetics granulomatous disease leishmaniasis visceral / immunology* pmid:10603400 pmc97133 doi:10.1128/iai.68.1.288-293.2000 h w murray s delph-etienne antimony / therapeutic use antiprotozoal agents / therapeutic use guanidines / pharmacology interferon-gamma / deficiency interferon-gamma / immunology* visceral / drug therapy* visceral / pathology liver / parasitology macrophages / immunology* nitric oxide synthase / antagonists & inhibitors nitric oxide synthase / deficiency nitric oxide synthase / genetics nitric oxide synthase type ii

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.