Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome

Clicks: 362
ID: 119028
2017
Free PDF
Article Quality & Performance Metrics
Overall Quality Improving Quality
0.0 /100
Combines engagement data with AI-assessed academic quality
AI Quality Assessment
Not analyzed
Abstract
Polycystic ovary syndrome (PCOS) is a complex hormonal disorder characterized by reproductive, endocrine, and metabolic abnormalities. As the origins of PCOS remain unknown, mechanism-based treatments are not feasible and current management relies on treatment of symptoms. Hyperandrogenism is the mo …
Reference Key
asl2017proceedingsneuroendocrine Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Caldwell ASL;Edwards MC;Desai R;Jimenez M;Gilchrist RB;Handelsman DJ;Walters KA;;
Journal Proceedings of the National Academy of Sciences of the United States of America
Year 2017
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/28320971
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female Disease Models animal* Cells Cultured Receptors Knockout polycystic ovary syndrome / metabolism polycystic ovary syndrome / pathology* neurons / drug effects neurons / metabolism androgens / pharmacology* melissa c edwards kirsty a walters pmid:28320971 pmc5402450 doi:10.1073/pnas.1616467114 aimee s l caldwell estrous cycle / drug effects granulosa cells / drug effects granulosa cells / metabolism granulosa cells / pathology* neurons / pathology* neurosecretory systems / drug effects* polycystic ovary syndrome / drug therapy androgen / physiology*

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.