Organic letters

Journal of enzyme inhibition and medicinal chemistry

Proceedings of the National Academy of Sciences of the United States of America

international immunopharmacology

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

the journal of physical chemistry a

Appetite

Future medicinal chemistry

insect biochemistry and molecular biology

biophysical chemistry

drug development research

cancer metastasis reviews

[1] Novel histone deacetylase inhibitors bearing a 4-piperidin-4-yl-triazole scaffold as antitumor agents.

[2] Atipamezole is a promising non-discriminative inhibitor against pan-CYP450 including diclofenac 4'-hydroxylation: A comparison with ABT for drug ADME optimization and mechanism study.

[3] Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site.

[4] Synthesis and human carbonic anhydrase I, II, VA, and XII inhibition with novel amino acid-sulphonamide conjugates.

[5] Spectra and Photorelaxation of Hydroxyphenyl-benzotriazole-Type UV Absorbers: From Monomers to Nanoparticles.

[6] Cobalt-Catalyzed Intermolecular Markovnikov Hydroamination of Nonactivated Olefins: -Selective Alkylation of Benzotriazole.

[7] Second generation 4,5,6,7-tetrahydrobenzo[]thiazoles as novel DNA gyrase inhibitors.

[8] Protonation states of central amino acids in a zinc metalloprotease complexed with inhibitor: Molecular mechanics optimizations and ab initio molecular orbital calculations.

[9] Inhibition of MAPKs Signaling Pathways Prevents Acrolein-Induced Neurotoxicity in HT22 Mouse Hippocampal Cells

[10] prospects for circumventing aminoglycoside kinase mediated antibiotic resistance

[11] a medicinal herb scutellaria lateriflora inhibits prp replication in vitro and delays the onset of prion disease in mice

[12] design, synthesis, and biological evaluation of axitinib derivatives

[13] inhibitory activities of alkyl syringates and related compounds on aflatoxin production

[14] pengaruh penambahan inhibitor alami terhadap laju korosi pada material pipa dalam larutan air laut buatan

[15] the process and strategy for developing selective histone deacetylase 3 inhibitors

[16] multiple chemical scaffolds inhibit a promising leishmania drug target

[17] handling anisotropy and strength of fiber-reinforced plastic via local inhibition of the curing process

[18] Acetylcholinesterase Inhibitory Activity and Chemical Composition of Commercial Essential Oils

[19] Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials

[20] Cholinesterase inhibitors for Alzheimer's disease

[21] Chalcones as potent tyrosinase inhibitors: the importance of a 2, 4-substituted resorcinol moiety

[22] Synthesis of benzophenone hydrazone analogs and their DPPH radical scavenging and urease inhibitory activities

[23] New piperidine-hydrazone derivatives: Synthesis, biological evaluations and molecular docking studies as AChE and BChE inhibitors

[24] Sulfonamide derivatives as inhibitors: in silico approach.

[25] Design, synthesis, and biological evaluation of selective and potent Carbazole-based butyrylcholinesterase inhibitors.

[26] Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2.

[27] Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors.

[28] Discovery of tetrahydrocarbazoles as dual pERK and pRb inhibitors.

[29] Synthesis, evaluation and molecular modelling studies of 2-(carbazol-3-yl)-2-oxoacetamide analogues as a new class of potential pancreatic lipase inhibitors.

[30] Purification and characterization of a cystatin like thiol protease inhibitor from Brassica nigra.

[31] The Critical Role of X Chromosome-linked Inhibitor of Apoptosis (XIAP) in Differential Synergism Induced by Pentachlorophenol and Copper-1,10-phenanthroline Complex in Normal and Cancer Liver Cells.

[32] Purification and characterization of a cystatin like thiol protease inhibitor from Brassica nigra

[33] Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant:  Lead Identification and SAR of 3- and 4-Substituted Derivatives

[34] Pharmacophores modeling in terms of prediction of theoretical physico-chemical properties and verification by experimental correlations of Carbacylamidophosphates (CAPh) and Sulfanylamidophosphates (SAPh) Tested as New Carbonic Anhydrase Inhibitors.

[35] EI-2346, a novel interleukin-1beta converting enzyme inhibitor produced by Streptomyces sp. E-2346. I. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties, and biological properties.

[36] Cyrmenins, new beta-methoxyacrylate inhibitors of the electron transport. Production, isolation, physico-chemical and biological properties.

[37] EI-1941-1 and -2, novel interleukin-1 beta converting enzyme inhibitors Produced by Farrowia sp. E-1941. II. Taxonomy of producing strain, fermentation, isolation, physico-chemical properties, and biological properties.

[38] Convenient framework of poly functionalized (E)-2-benzylideno-(Z)-carbazolylideno cyanoacetamides via rearrangements as an efficient antibiofilm inhibitors with SAR study.

[39] A quantitative proteomic analysis of cofilin phosphorylation in myeloid cells and its modulation using the LIM kinase inhibitor Pyr1.

[40] Design and synthesis of 3-(3-((9 H-carbazol-4-yl)oxy)-2-hydroxypropyl)-2-phenylquinazolin-4(3 H)-one derivatives to induce ACE inhibitory activity

[41] Inhibitory effects of two types of food additives on biofilm formation by foodborne pathogens.

[42] Phenolic profile, antioxidant and enzyme inhibitory activities of Ottelia acuminata, an endemic plant from southwestern China

[43] Cholinesterase inhibitors as Alzheimer's therapeutics (Review).

[44] Synthesis and biological evaluation of indoloquinoline alkaloid cryptolepine and its bromo-derivative as dual cholinesterase inhibitors.

[45] Use of Cholinesterase Inhibitors in Non-Alzheimer's Dementias.

[46] Tubes for detection of cholinesterase inhibitors-Unique effects of Neusilin on the stability of butyrylcholinesterase-impregnated carriers.

[47] Coumarin derivatives as acetyl- and butyrylcholinestrase inhibitors: An in vitro, molecular docking, and molecular dynamics simulations study.

[48] Optimization of ultrasound-assisted extraction of total phenolic contents and antioxidant activity using response surface methodology from jujube leaves (Ziziphus jujuba) and evaluation of anticholinesterase inhibitory activity

[49] Acute Rat and Mouse Oral Toxicity Determination of Anticholinesterase Inhibitor Carbamate Pesticides: A QSTR Approach

[50] Flavone glycosides from Sicyos angulatus and their inhibitory effects on hepatic lipid accumulation.

[51] DPP-IV Inhibitory Potentials of Flavonol Glycosides Isolated from the Seeds of : In Vitro and Analyses.

[52] Flavonol glycosides with α-Glucosidase inhibitory activities and new flavone C-diosides from the leaves of machilus konishii

[53] Lysozyme-luteolin binding: molecular insights into the complexation process and the inhibitory effects of luteolin towards protein modification.

[54] Synthesis, biological evaluation and docking studies of chalcone and flavone analogs as antioxidants and acetylcholinesterase inhibitors

[55] Investigation of potent inhibitors of cholinesterase based on thiourea and pyrazoline derivatives: Synthesis, inhibition assay and molecular modeling studies.

[56] Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-α Motif Kinase (ZAK) Inhibitors.

[57] Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors.

[58] Inhibitory effects of leaf extract of on and characterization of novel inhibitory compounds by GC-MS analysis.

[59] Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment.

[60] Novel morpholine containing cinnamoyl amides as potent tyrosinase inhibitors.

[61] To detect the minimum inhibitory concentration and time-kill curve of shiitake mushroom on periodontal pathogens: An study.

[62] Discovery of tropinone-thiazole derivatives as potent caspase 3/7 activators, and noncompetitive tyrosinase inhibitors with high antiproliferative activity: Rational design, one-pot tricomponent synthesis, and lipophilicity determination.

[63] Phase Ib study of the combination of pexidartinib (PLX3397), a CSF-1R inhibitor, and paclitaxel in patients with advanced solid tumors.

[64] Augmentation of the therapeutic efficacy of WEE1 kinase inhibitor AZD1775 by inhibiting the YAP–E2F1–DNA damage response pathway axis

[65] PIM kinase inhibitors: Structural and pharmacological perspectives.

[66] Primary antiphospholipid syndrome during aromatase inhibitors therapy: A case report and review of the literature.

[67] "Favoring my playmate seems fair": Inhibitory control and theory of mind in preschoolers' self-disadvantaging behaviors.

[68] Erratum to "Are All Oral COX-2 Selective Inhibitors the Same? A Consideration of Celecoxib, Etoricoxib, and Diclofenac".

[69] Comparison on total phenols content and antioxidant activity and inhibitory effect on α-glucosidase activity of water chestnut shells (Trapa natans shells) from different locations

[70] Evaluation of extracellular polymeric substances extracted from waste activated sludge as a renewable corrosion inhibitor.

[71] Synthesis, activity testing and molybdenum(VI) complexation of Schiff bases derived from 2,4,6-trihydroxybenzaldehyde investigated as xanthine oxidase inhibitors.

[72] Synthesis and structure elucidation of 2,3,5,6,7,8-hexahydro-1 H-[1,2,4]triazolo[1,2-a]pyridazine-1-thione, 3,3-disubstituted and 2-substituted derivatives and evaluation of their inhibitory activity against inducible nitric oxide synthase.

[73] In vitro activity of a Hos2 deacetylase inhibitor, MGCD290, in combination with echinocandins against echinocandin-resistant Candida species.

[74] 3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors.

[75] Synthesis and anticancer evaluation of novel triazole linked N-(pyrimidin-2-yl)benzo[d]thiazol-2-amine derivatives as inhibitors of cell survival proteins and inducers of apoptosis in MCF-7 breast cancer cells.

[76] Acid-mediated synthesis of fully substituted 1,2,3-triazoles: Multicomponent coupling reactions, mechanistic study, synthesis of serine hydrolase inhibitor and its derivatives

[77] Discovery and biological evaluation of novel 6,7-disubstituted-4-(2-fluorophenoxy)quinoline derivatives possessing 1,2,3-triazole-4-carboxamide moiety as c-Met kinase inhibitors

[78] Evaluating the antioxidant and acetylcholinesterase inhibitory activity of three Centaurea species

[79] α-Glucosidase inhibitory activity and in vivo antihyperglycemic effect of secondary metabolites from the leaf infusion of Ocimum campechianum mill.

[80] Isolation of Chemical Constituents of Centaurea virgata Lam. and Xanthine Oxidase Inhibitory Activity of the Plant Extract and Compounds.

[81] Screening for antioxidant and antimutagenic properties of extracts from centaurea pterocaula as well as their enzyme inhibitory potentials

[82] Antioxidant, Anti-Inflammatory, Acetylcholinesterase Inhibitory and Antimicrobial Activities of Turkish Endemic Centaurea antiochia var. Praealta

[83] Centaurea karduchorum Boiss. from Eastern Anatolia: Phenolic composition, antioxidant and enzyme inhibitory activities

[84] Pharmacological characterization of the seven human NOX isoforms and their inhibitors.

[85] Protective effects of Gαq-RGS2 signaling inhibitor in aminophylline induced cardiac arrhythmia.

[86] Inhibitory Effect of Epigallocatechin Gallate, Epigallocatechin, and Gallic Acid on the Formation of N-Nitrosodiethylamine In Vitro.

[87] Effects of nitrification inhibitors on gross N nitrification rate, ammonia oxidizers, and NO production under different temperatures in two pasture soils.

[88] Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity.

[89] An Unexpected Degradation Pathway of a 1,2,4-Triazolo[4,3-a]pyridine Derivative: The Formation of 2 Cationic Pseudodimers of an 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor Drug Candidate in a Stressed Capsule Formulation.

[90] Synthesis and Thrombin, Factor Xa and U46619 Inhibitory Effects of Non-Amidino and Amidino N²-Thiophenecarbonyl- and N²-Tosylanthranilamides.

[91] Autoinhibitory properties of the parent but not of the N-oxide metabolite contribute to infusion rate-dependent voriconazole pharmacokinetics.

[92] Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas.

[93] Novel iminobenzoxathiolone compound inhibits nuclear factor-kappaB activation targeting inhibitory kappaB kinase beta and down-regulating interleukin-1beta expression in lipopolysaccharide-activated macrophages.

[94] Co-crystalization and in vitro biological characterization of 5-aryl-4-(5-substituted-2-4-dihydroxyphenyl)-1,2,3-thiadiazole Hsp90 inhibitors.

[95] Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1H-pyrazole as highly selective and potent BRAFV600E and CRAF inhibitor

[96] Synthesis and evaluation of tetrahydropyrazolopyridine inhibitors of anion exchange protein SLC26A4 (pendrin).

[97] Synthesis and Evaluation of Novel Pyrazole Ethandiamide Compounds as Inhibitors of Human THP-1 Monocytic Cell Neurotoxicity.

[98] Novel Pyrazoloquinolin-2-ones: Design, synthesis, docking studies, and biological evaluation as antiproliferative EGFR-TK inhibitors.

[99] Design, synthesis and anticervical cancer activity of new benzofuran-pyrazol-hydrazono- thiazolidin-4-one hybrids as potential EGFR inhibitors and apoptosis inducing agents.

[100] Design, synthesis and biological evaluation of 2-H pyrazole derivatives containing morpholine moieties as highly potent small molecule inhibitors of APC–Asef interaction

[101] Synthesis and biological evaluation of purine-pyrazole hybrids incorporating thiazole, thiazolidinone or rhodanine moiety as 15-LOX inhibitors endowed with anticancer and antioxidant potential