cryo-em

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1
Cryo-EM structure of pleconaril-resistant rhinovirus-B5 complexed to the antiviral OBR-5-340 reveals unexpected binding site.
Wald, Jiri;Pasin, Marion;Richter, Martina;Walther, Christin;Mathai, Neann;Kirchmair, Johannes;Makaro...
2019 Proceedings of the National Academy of Sciences of... DOI: 10.1073/pnas.1904732... 240 views
2
Cryo-electron Microscopy Structure of the Acinetobacter baumannii 70S Ribosome and Implications for New Antibiotic Development.
Morgan, Christopher E;Huang, Wei;Rudin, Susan D;Taylor, Derek J;Kirby, James E;Bonomo, Robert A;Yu,...
2020 mBio DOI: e03117-19 378 views
3
A Super-Clustering Approach for Fully Automated Single Particle Picking in Cryo-EM.
Al-Azzawi, Adil;Ouadou, Anes;Tanner, John J;Cheng, Jianlin;
2019 genes DOI: E666 160 views
4
Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation.
Johnson, Matthew C;Kollman, Justin M;
2020 eLife DOI: 10.7554/eLife.53243 275 views
5
Structural and Biochemical Characterization of the nsp12-nsp7-nsp8 Core Polymerase Complex from SARS-CoV-2.
Peng, Qi;Peng, Ruchao;Yuan, Bin;Zhao, Jingru;Wang, Min;Wang, Xixi;Wang, Qian;Sun, Yan;Fan, Zheng;Qi,...
2020 Cell reports DOI: S2211-1247(20)30754-... 185 views

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eLife
ISSN: 2050-084X 779 views
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ISSN: 2211-1247 681 views

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inhibitor 3d structure capsid binder rhinovirus antibiotic resistance structural biology 70s ribosome acinetobacter baumannii k-means micrograph fuzzy c-means (fcm) intensity based clustering (ibc) protein structure determination singe particle pickling super-clustering E. coli human metabolism molecular biophysics allostery