polypharmacology

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1
Synergistic drug combination effectively blocks Ebola virus infection.
Sun, Wei;He, Shihua;Martínez-Romero, Carles;Kouznetsova, Jennifer;Tawa, Gregory;Xu, Miao;Shinn, Paul...
2017 Antiviral research DOI: 10.1016/j.antiviral.... 233 views
2
Polypharmacology Approach Against Migraine with Aura and Brain Edema for the Development of an Efficient Inhibitor and its Analogues.
Rizwan, Samawia;Mehmood, Asim;Khalid, Irum;Khan, Muhammad Saad;Yousafi, Qudsia;Kalsoom, Saima;Rashid...
2018 current computer-aided drug design DOI: 10.2174/157340991466... 251 views
3
A systematic review of the role of the nociceptin receptor system in stress, cognition, and reward: relevance to schizophrenia.
Khan, Muhammad Saad;Boileau, Isabelle;Kolla, Nathan;Mizrahi, Romina;
2018 Translational Psychiatry DOI: 10.1038/s41398-017-0... 296 views
4
Reply.
Elbaz, Uri;Mireskandari, Kamiar;Tehrani, Nasrin;Shen, Carl;Khan, Muhammad Saad;Williams, Sara;Ali, A...
2017 American journal of ophthalmology DOI: S0002-9394(17)30124-... 222 views
5
Structure-based design and optimization of pyrimidine- and 1,2,4-triazolo[4,3-a]pyrimidine-based matrix metalloproteinase-10/13 inhibitors via Dimroth rearrangement towards targeted polypharmacology.
El Ashry, El Sayed Helmy;Awad, Laila Fathy;Teleb, Mohamed;Ibrahim, Nihal Ahmed;Abu-Serie, Marwa M;Ab...
2020 Bioorganic chemistry DOI: S0045-2068(19)31828-... 263 views
6
Corrigendum to "The modulating effect of lipid bilayer/p-coumaric acid interactions on electrical properties of model lipid membranes and human glioblastoma cells" [Bioorg. Chem. 92 (2019) 103242].
Naumowicz, Monika;Kusaczuk, Magdalena;Kruszewski, Marcin Andrzej;Gál, Miroslav;Krętowski, Rafał;Cech...
2020 Bioorganic chemistry DOI: S0045-2068(20)30157-... 252 views
7
Turning liabilities into opportunities: Off-target based drug repurposing in cancer.
Palve, Vinayak;Liao, Yi;Remsing Rix, Lily L;Rix, Uwe;
2020 seminars in cancer biology DOI: S1044-579X(20)30036-... 302 views

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drug combination drug repurposing ebola prevention ebola treatment Docking migraine analogues edema superimposition. anticancer pyrimidine triazolopyrimidine dimroth rearrangement mmp-10/13 precision medicine targeted cancer therapy off-target