gene targeting

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1
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
Hayhurst GP;Lee YH;Lambert G;Ward JM;Gonzalez FJ;;
2001 molecular and cellular biology 370 views
2
CRISPR-Cas immunity against phages: its effects on the evolution and survival of bacterial pathogens
Marraffini LA;;
2013 PLoS pathogens 228 views
3
RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function
Lee JY;Ristow M;Lin X;White MF;Magnuson MA;Hennighausen L;;
2006 The Journal of biological chemistry 219 views
4
IL-1 receptor accessory protein is an essential component of the IL-1 receptor
Cullinan EB;Kwee L;Nunes P;Shuster DJ;Ju G;McIntyre KW;Chizzonite RA;Labow MA;;
1998 Journal of immunology (Baltimore, Md. : 1950) 214 views
5
Roles for Nkx3.1 in prostate development and cancer
Bhatia-Gaur R;Donjacour AA;Sciavolino PJ;Kim M;Desai N;Young P;Norton CR;Gridley T;Cardiff RD;Cunha...
1999 genes & development 218 views
6
[Corrigendum] Alterations in gene expression during sexual differentiation in androgen receptor knockout mice induced by environmental endocrine disruptors.
Liu, Dehong;Shen, Liping;Tao, Yonglin;Kuang, Ying;Cai, Lei;Wang, Dan;He, Meiduo;Tong, Xuebo;Zhou, Sh...
2019 international journal of molecular medicine DOI: 10.3892/ijmm.2019.42... 305 views
7
Enhanced scale and scope of genome engineering and regulation using CRISPR/Cas in Saccharomyces cerevisiae.
Deaner, Matthew;Alper, Hal S;
2019 fems yeast research DOI: foz076 275 views
8
The application of the CRISPR-Cas9 system in pv. actinidiae.
Ho, Joycelyn;Zhao, Min;Wojcik, Samuel;Taiaroa, George;Butler, Margi;Poulter, Russell;
2020 Journal of medical microbiology DOI: 10.1099/jmm.0.001124 261 views
9
CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1
Guillen, R.X.
2020 Scientific reports DOI: 10.1038/s41598-020-6... 178 views
10
Of Mice and Men, Redux: Modern Challenges in β Cell Gene Targeting
Estall, Jennifer L;Screaton, Robert A;
2020 endocrinology 108 views
11
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
Kubota N;Terauchi Y;Miki H;Tamemoto H;Yamauchi T;Komeda K;Satoh S;Nakano R;Ishii C;Sugiyama T;Eto K;...
1999 molecular cell 430 views
12
advances in genetic engineering of domestic animals
;Shaohua WANG,Kun ZHANG,Yunping DAI
2016 archiv fur rechts- und sozialphilosophie DOI: 10.15302/J-FASE-2016... 209 views
13
high-fidelity glucagon-creer mouse line generated by crispr-cas9 assisted gene targeting
;Amanda M. Ackermann;Jia Zhang;Aryel Heller;Anna Briker;Klaus H. Kaestner
2017 Small (Weinheim an der Bergstrasse, Germany) 206 views
14
inducing fungus-resistance into plants through biotechnology
;Shabir Hussain WANI
2010 annals of academy of romanian scientists series on... 176 views
15
the gene targeting approach of small fragment homologous replacement (sfhr) alters the expression patterns of dna repair and cell cycle control genes
;Silvia Pierandrei;Andrea Luchetti;Massimo Sanchez;Giuseppe Novelli;Federica Sangiuolo;Marco Lucarel...
2016 coordination chemistry reviews DOI: 10.1038/mtna.2016.2 195 views
16
crispr/cas9-aav mediated knock-in at nrl locus in human embryonic stem cells
;Xianglian Ge;Haitao Xi;Fayu Yang;Xiao Zhi;Yanghua Fu;Ding Chen;Ren-He Xu;Ge Lin;Jia Qu;Junzhao Zhao...
2016 coordination chemistry reviews DOI: 10.1038/mtna.2016.10... 196 views
17
a hyperactive transposase promotes persistent gene transfer of a piggybac dna transposon
;Erin R Burnight;Janice M Staber;Pavel Korsakov;Xianghong Li;Benjamin T Brett;Todd E Scheetz;Nancy L...
2012 coordination chemistry reviews DOI: 10.1038/mtna.2012.12 174 views
18
precise genome modification via sequence-specific nucleases-mediated gene targeting for crop improvement
;Yongwei Sun;Jingying Li;Lanqin Xia
2016 phytochemistry letters DOI: 10.3389/fpls.2016.01... 146 views
19
detection and phylogenetic analysis of coastal bioaerosols using culture dependent and independent techniques
;R. Urbano;B. Palenik;C. J. Gaston;K. A. Prather
2011 tetrahedron letters DOI: 10.5194/bg-8-301-201... 158 views
20
Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA
Kobielak , Krzysztof;Pasolli , H. Amalia;Alonso , Laura;Polak , Lisa;Fuchs , Elaine;
2003 journal of cell biology DOI: 10.1083/jcb.20030904... 123 views

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National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine phenotype Receptors Transcription Factors / metabolism* Base Sequence Active Y H Lee Liver / metabolism* Knockout cell differentiation