RIP-Cre revisited, evidence for impairments of pancreatic beta-cell function

Clicks: 246
ID: 270179
2006
Free PDF
Article Quality & Performance Metrics
Overall Quality Improving Quality
0.0 /100
Combines engagement data with AI-assessed academic quality
AI Quality Assessment
Not analyzed
Abstract
The Cre/loxP recombinase system for performing conditional gene targeting experiments has been very useful in exploring genetic pathways that control both the development and function of pancreatic beta-cells. One particular line of transgenic mice (B6.Cg-Tg(Ins2-cre)25Mgn/J), commonly called RIP-Cr …
Reference Key
jy2006therip-cre Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lee JY;Ristow M;Lin X;White MF;Magnuson MA;Hennighausen L;;
Journal The Journal of biological chemistry
Year 2006
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/16326700
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female male Rats Promoter Regions transgenic gene targeting insulin-secreting cells / pathology insulin-secreting cells / physiology* pmid:16326700 doi:10.1074/jbc.m512373200 ji-yeon lee michael ristow lothar hennighausen glucose intolerance / genetics insulin / genetics* integrases / genetics*

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.