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Journal of medicinal chemistry

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scopus ncbi ulakbim sci
Short Name J Med Chem
Abbreviated Name j med chem
ISSN 1520-4804
Aim and Scope
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Publications Per Year

Recent Articles (122 total)

2019
Design, Synthesis, and Structure-Activity Relationships of 1,2,3-Triazole Benzenesulfonamides as New Selective Leucine-Zipper and Sterile-ฮฑ Motif Kinase (ZAK) Inhibitors.
Yang, Jianzhang;Shibu, Marthandam Asokan;Kong, Lulu;Luo, Jinfeng;BadrealamKhan, Farheen;Huang, Yanhui;Tu, Zheng-Chao;Yun, Cai-Hong;Huang, Chih-Yang;Ding, Ke;Lu, Xiaoyun;
430 views DOI Abstract
2000
Novel 1,5-Diphenylpyrazole Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors with Enhanced Activity versus the Delavirdine-Resistant P236L Mutant:โ€‰ Lead Identification and SAR of 3- and 4-Substituted Derivatives
Genin, Michael J.;Biles, Carolyn;Keiser, Barb J.;Poppe, Susan M.;Swaney, Steven M.;Tarpley, W. Gary;Yagi, Yoshihiko;Romero, Donna L.
Vol. 43 , No. 5 , pp. 1034-1040
419 views DOI Abstract
1993
Antiviral activity of C-alkylated purine nucleosides obtained by cross-coupling with tetraalkyltin reagents
Van Aerschot AA;Mamos P;Weyns NJ;Ikeda S;De Clercq E;Herdewijn PA;;
Vol. 36 , No. 20 , pp. -
356 views Abstract
2012
Design, synthesis, and structure-activity correlations of novel dibenzo[b,d]furan, dibenzo[b,d]thiophene, and N-methylcarbazole clubbed 1,2,3-triazoles as potent inhibitors of Mycobacterium tuberculosis.
Patpi, Santhosh Reddy;Pulipati, Lokesh;Yogeeswari, Perumal;Sriram, Dharmarajan;Jain, Nishant;Sridhar, Balasubramanian;Murthy, Ramalinga;Anjana Devi, T;Kalivendi, Shasi Vardhan;Kantevari, Srinivas;
Vol. 55 , No. 8 , pp. 3911-22
354 views DOI Abstract
2019
Linker Optimization and Therapeutic Evaluation of Phosphatidylserine-Targeting Zinc Dipicolylamine-based Drug Conjugates.
Liu, Yu-Wei;Chen, Yun-Yu;Hsu, Chia-Yu;Chiu, Tai-Yu;Liu, Kuan-Liang;Lo, Chen-Fu;Fang, Ming-Yu;Huang, Yu-Cheng;Yeh, Teng-Kuang;Pak, Koon Y;Gray, Brian D;Hsu, Tsu-An;Huang, Kuan-Hsun;Shih, Chuan;Shia, Kak-Shan;Chen, Chiung-Tong;Tsou, Lun K;
353 views DOI Abstract
1995
Synthesis and antiviral activity of benzyl-substituted imidazo [1,5-a]-1,3,5-triazine (5,8-diaza-7,9-dideazapurine) derivatives
Golankiewicz B;Januszczyk P;Ikeda S;Balzarini J;De Clercq E;;
Vol. 38 , No. 18 , pp. -
338 views Abstract
2019
Triazole Bridged Flavonoid Dimers as Potent, Nontoxic, and Highly Selective Breast Cancer Resistance Protein (BCRP/ABCG2) Inhibitors.
Zhu, Xuezhen;Wong, Iris L K;Chan, Kin-Fai;Cui, Jiahua;Law, Man Chun;Chong, Tsz Cheung;Hu, Xuesen;Chow, Larry M C;Chan, Tak Hang;
Vol. 62 , No. 18 , pp. 8578-8608
336 views DOI Abstract
2019
Structure Kinetics Relationships and Molecular Dynamics show crucial role for heterocycle leaving group in irreversible diacylglycerol lipase inhibitors.
Janssen, Antonius P A;Hengst, Jacob van;Bรฉquignon, Olivier;Deng, Hui;Westen, Gerard van;van der Stelt, Mario;
330 views DOI Abstract
2019
Fragment-Based Discovery of a Qualified Hit Targeting the Latency-Associated Nuclear Antigen of the Oncogenic Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8
Kirsch, P.
Vol. 62 , pp. 3924-3939
329 views DOI
2019
Inhibition Mechanisms of Indoleamine 2,3-Dioxygenase 1 (IDO1).
Rรถhrig, Ute Friederike;Reynaud, Aline;Majjigapu, Somi Reddy;Vogel, Pierre;Pojer, Florence;Zoete, Vincent;
327 views DOI Abstract
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