Synthesis and antiviral activity of benzyl-substituted imidazo [1,5-a]-1,3,5-triazine (5,8-diaza-7,9-dideazapurine) derivatives

Clicks: 437
ID: 119801
1995
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Star

Ranked #6 of 122 articles by views in Journal of medicinal chemistry

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 122 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
A variety of imidazo[1,5-a]-1,3,5-triazine derivatives carrying C-, O-, and S-benzyl and/or 4-methylbenzyl groups were synthesized and examined for their inhibitory effects on the replication of ortho- and paramyxoviruses. The key compounds 8-R-2-thioxo-2,3-dihydroimidazo [1,5-a]-1,3,5-triazin-4(1H) …
Reference Key
b1995journalsynthesis Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Golankiewicz B;Januszczyk P;Ikeda S;Balzarini J;De Clercq E;;
Journal Journal of medicinal chemistry
Year 1995
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/7658442
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't cell line chlorocebus aethiops vero cells e de clercq antiviral agents / pharmacology* hela cells hiv-1 / drug effects hiv-2 / drug effects human / drug effects respiratory syncytial viruses / drug effects structure-activity relationship parainfluenza virus 3 influenza a virus / drug effects pmid:7658442 doi:10.1021/jm00018a015 b golankiewicz p januszczyk antiviral agents / chemical synthesis drug screening assays antitumor imidazoles / chemical synthesis imidazoles / pharmacology* rna viruses / drug effects triazines / chemical synthesis triazines / pharmacology*

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.