nanoparticles for control of biofilms of acinetobacter species

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ID: 194399
2016
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Abstract
Biofilms are the cause of 80% of microbial infections. Acinetobacter species have emerged as multi- and pan-drug-resistant bacteria and pose a great threat to human health. These act as nosocomial pathogens and form excellent biofilms, both on biotic and abiotic surfaces, leading to severe infections and diseases. Various methods have been developed for treatment and control of Acinetobacter biofilm including photodynamic therapy, radioimmunotherapy, prophylactic vaccines and antimicrobial peptides. Nanotechnology, in the present scenario, offers a promising alternative. Nanomaterials possess unique properties, and multiple bactericidal mechanisms render them more effective than conventional drugs. This review intends to provide an overview of Acinetobacter biofilm and the significant role of various nanoparticles as anti-biofouling agents, surface-coating materials and drug-delivery vehicles for biofilm control and treatment of Acinetobacter infections.
Reference Key
singh2016materialsnanoparticles Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors ;Richa Singh;Shradhda Nadhe;Sweety Wadhwani;Utkarsha Shedbalkar;Balu Ananda Chopade
Journal Nature Materials
Year 2016
DOI
10.3390/ma9050383
URL
http://www.mdpi.com/1996-1944/9/5/383
Keywords
biofilm Drug resistance nanoparticles acinetobacter electronics civil engineering (general)microscopydescriptive and experimental mechanics nuclear engineeringengineering (general)

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