European journal of medicinal chemistry

Bioorganic & medicinal chemistry letters

anti-cancer agents in medicinal chemistry

[1] Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: synthesis, anti-invasive and anti-angiogenic properties.

[2] Substitution at Phenyl Rings of Chalcone and Schiff Base Moieties Accounts for their Antiproliferative Activity.

[3] (e)-3-methyl-6-(3-oxo-3-(3,4,5-trimethoxyphenyl)prop-1-en-1-yl)-2(3h)-benzothiazolone

[4] synthesis and antibacterial studies of some novel isoxazoline derivatives

[5] chemically synthesized glycosides of hydroxylated flavylium ions as suitable models of anthocyanins: binding to iron ions and human serum albumin, antioxidant activity in model gastric conditions

[6] (e)-3-(2,5-difluorophenyl)-1-phenylprop-2-en-1-one

[7] synthesis and antibacterial activity of some heterocyclic chalcone analogues alone and in combination with antibiotics

[8] synthesis and regioselective reaction of some unsymmetrical heterocyclic chalcone derivatives and spiro heterocyclic compounds as antibacterial agents

[9] Chalcones as potent tyrosinase inhibitors: the importance of a 2, 4-substituted resorcinol moiety

[10] Synthesis, biological evaluation and docking studies of chalcone and flavone analogs as antioxidants and acetylcholinesterase inhibitors

[11] First Total Synthesis of Original Chalcone–Flavone Dimers as Cissampeloflavone Analogues

[12] Influence of S-Oxidation on Cytotoxic Activity of Oxathiole-Fused Chalcones.

[13] Structural factors affecting affinity of cytotoxic oxathiole-fused chalcones toward tubulin.

[14] Antifungal action of the oxathiolone-fused chalcone derivative.

[15] Anti-cancer potential of novel glycosylated 1,4-substituted triazolylchalcone derivatives.

[16] Correction: A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by chalcone derivatives.

[17] Synthesis and heme polymerization inhibitory activity (Hpia) assay of chalcone, flavone and flavanone derivatives

[18] Ultrasound-promoted synthesis of flavones by oxidation of 2’-hydroxychalcones and flavanones using I2/DMSO

[19] Improved Synthesis of 2',6'-Dihydroxy-3,4-dimethoxy Chalcone by Grinding Technique to Synthesize 5-Hydroxy-3',4'-dimethoxy Flavone

[20] Naringin-Chalcone Bioflavonoid-Protected Nanocolloids: Mode of Flavonoid Adsorption, a Determinant for Protein Extraction.

[21] Novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitor: synthesis, anti-invasive and anti-angiogenic properties.

[22] Gas/Liquid-Phase Micro-Flow Trifluoromethylation using Fluoroform: Trifluoromethylation of Aldehydes, Ketones, Chalcones, and -Sulfinylimines.

[23] Chalcones as a basis for computer-aided drug design: innovative approaches to tackle malaria.

[24] Synthesis, characterization and antibacterial activity of some new of novel 1,2,3-triazole-chalcone derivatives from N-acetyl-5H-dibenzo [B,F] azepine-5-carboxamide

[25] A strategic approach to the synthesis of ferrocene appended chalcone linked triazole allied organosilatranes: Antibacterial, antifungal, antiparasitic and antioxidant studies

[26] 2,4-Dihydroxy-3'-methoxy-4'-ethoxychalcone suppresses cell proliferation and induces apoptosis of multiple myeloma via the PI3K/akt/mTOR signaling pathway

[27] Chalcone derivatives targeting mitosis: synthesis, evaluation of antitumor activity and lipophilicity.

[28] On Efficient Synthesis, X-Ray Analysis and DPPH Radical Scavenging Activity of Pyrazolone-Based trans-Chalcones

[29] Sulphonamide chalcones: Conformationally diverse yet optically similar

[30] Microwave Assisted Synthesis, Characterization and Biological Activities of Ferrocenyl Chalcones and Their QSAR Analysis.

[31] A step-by-step synthesis of triazole-benzimidazole-chalcone hybrids: Anticancer activity in human cells⁺

[32] Computational investigations and molecular dynamics simulations envisioned for potent antioxidant and anticancer drugs using indole-chalcone-triazole hybrids

[33] Molecular Docking Study, Cytotoxicity, Cell Cycle Arrest and Apoptotic Induction of Novel Chalcones Incorporating Thiadiazolyl Isoquinoline in Cervical Cancer.

[34] Substitution at Phenyl Rings of Chalcone and Schiff Base Moieties Accounts for their Antiproliferative Activity.

[35] Facile synthesis of vanillin-based novel bischalcones identifies one that induces apoptosis and displays synergy with Artemisinin in killing chloroquine resistant Plasmodium falciparum

[36] Design, economical synthesis and antiplasmodial evaluation of vanillin derived allylated chalcones and their marked synergism with artemisinin against chloroquine resistant strains of Plasmodium falciparum

[37] Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.

[38] Design, synthesis, in-silico and biological evaluation of novel chalcone derivatives as multi-function agents for the treatment of Alzheimer's disease.

[39] syntheses of 4-indolylquinoline derivatives via reductive cyclization of indolylnitrochalcone derivatives by fe/hcl

[40] 4-hydroxychalcone attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice

[41] Design of Mn(II), Fe(III) and Ru(III) chalcone complexes: Structural elucidation, spectral, thermal and catalytic activity studies

[42] an efficient rucl3·h2o/i2 catalytic system: a facile access to 3-aroylimidazo[1,2-a]pyridines from 2-aminopyridines and chalcones

[43] atividade alelopática de chalcona sintética, de seus precursores e de cetonas e aldeídos relacionados allelopathic activity of synthetic chalcone, its precursors and of related cetones and aldehydes

[44] continuous-flow synthesis of deuterium-labeled antidiabetic chalcones: studies towards the selective deuteration of the alkynone core

[45] identification of bichalcones as sirtuin inhibitors by virtual screening and in vitro testing

[46] synthesis of 2-pyrazolines from pyridine based chalcone by conventional and microwave techniques: their comparison and antimicrobial studies

[47] antimalarial activity of 4-metoxychalcones: docking studies as falcipain/plasmepsin inhibitors, admet and lipophilic efficiency analysis to identify a putative oral lead candidate

[48] novel pyrazine analogs of chalcones: synthesis and evaluation of their antifungal and antimycobacterial activity

[49] catalytic hydrogenation reaction of naringin-chalcone. study of the electrochemical reaction

[50] in vitro anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin a, a chalcone isolated from boesenbergia rotunda (l.) (fingerroot)

[51] protective role of licochalcone b against ethanol-induced hepatotoxicity through regulation of erk signaling

[52] hepatoprotective effects of licochalcone b on carbon tetrachloride-induced liver toxicity in mice

[53] synthesis and antibacterial activity of some heterocyclic chalcone analogues alone and in combination with antibiotics

[54] synthesis and regioselective reaction of some unsymmetrical heterocyclic chalcone derivatives and spiro heterocyclic compounds as antibacterial agents

[55] Flavonoids, chalcones and phenyl-propanoids in apple and pear flowers

[56] Ameliorative effect of Boesenbergin A, a chalcone isolated from Boesenbergia rotunda (Fingerroot) on oxidative stress and inflammation in ethanol-induced gastric ulcer in vivo.

[57] Cardamonin (2',4'-dihydroxy-6'-methoxychalcone) isolated from Boesenbergia rotunda (L.) Mansf. inhibits CFA-induced rheumatoid arthritis in rats.

[58] Bifunctional Derivative of p,p'-Dichlorochalcone. Part II. Synthesis of a Novel Compound 2-[2-Carboxymethylthio-2-(4-chlorophenyl)ethyl]-2-(4-chlorophenyl)-4-thiazolidinone