thiazolidinone

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1
Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines.
Aziz, Marian W;Kamal, Aliaa M;Mohamed, Khaled O;Elgendy, Adel A;
2021 Bioorganic & medicinal chemistry letters DOI: S0960-894X(21)00213-... 311 views
2
Discovery of 4-((4-(4-(3-(2-(2,6-difluorophenyl)-4-oxothiazolidin-3-yl)ureido)-2-fluorophenoxy)-6-methoxyquinolin-7-yl)oxy)-N,N-diethylpiperidine-1-carboxamide as kinase inhibitor for the treatment of colorectal cancer.
Zhou, Yuting;Xu, Xingwei;Wang, Fei;He, Huan;Qi, Baohui;
2021 Bioorganic chemistry DOI: S0045-2068(20)31809-... 249 views
3
Unearthing novel thiazolidinone building blocks as carboxylic acid bioisosteres.
Scanlon, James J;Wren, Stephen P;
2020 Future medicinal chemistry DOI: 10.4155/fmc-2020-019... 110 views
4
Synthesis and biological evaluation of some coumarin hybrids as selective carbonic anhydrase IX and XII inhibitors.
Thacker, Pavitra S;Sridhar Goud, Nerella;Argulwar, Omkar S;Soman, Jyothsna;Angeli, Andrea;Alvala, Ma...
2020 Bioorganic chemistry DOI: S0045-2068(20)31570-... 206 views

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EGFR cytotoxic activity quinazolinone 3dqsar pharmacophore synthesis colorectal cancer design tyrosine kinase inhibitors quinoline bioisostere building blocks carboxylic acid pyrazole coumarin 1, 2, 3-triazole carbonic anhydrases hca ix & xii isoform