Two new glucoside derivatives of truxinic and cinnamic acids from mill.
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2019
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Abstract
A phytochemical investigations on the -butanol fraction of Mill. residues resulted in the isolation of ten compounds, including two new ones, 4,4'dimethoxy-2,2'di---d-glucopyranosyl-truxinate () and 2-(-d-glucosyloxy)--cinnamic acid butyl ester (), along with eight known compounds. The structures of compounds were confirmed by NMR and HR-ESI-MS techniques and comparison with published data. The NMR data for were attributed for the first time. Compound was proofed to be a natural compound in plant rather than a butyl ester artifact formed by esterification reaction with butanol by comparative HPLC-DAD analysis with the ethanol extract which was obtained prior to the application of butanol. All isolated compounds were evaluated for their antioxidant and anti-hypoglycaemic activities. Among them, compounds and showed strong anti-oxidant activities against DPPH with IC values of 12.99 and 31.74 M, respectively. Compound exhibited moderate inhibitory activity against PTP1B with an IC value of 31.28 M.
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ablikim2019twonatural
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| Authors | Ablikim, Gulnigar;Bobakulov, Khayrulla;Li, Jun;Yadikar, Nigary;Aisa, H A; |
| Journal | Natural product research |
| Year | 2019 |
| DOI |
10.1080/14786419.2019.1684283
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