reference materials and representative test materials to develop nanoparticle characterization methods: the nanochop project case
Clicks: 261
ID: 183688
2015
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This
article has not been analysed, so there is no overall score —
reader engagement is measured and shown alongside.
Reader Engagement
Popular Article
30.0
/100
261 views
22 readers
AI Quality Assessment
Not analyzed
Readership in this journal
PopularRanked #33 of 57 articles by views in spatium
Most read
Least read
Bar heights use a square-root scale.
Mint this article as an NFT
Not yet mintedCreate a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.
5
SUSD
one-off · no wallet required
Abstract
This paper describes the production and characteristics of the nanoparticle test materials prepared for common use in the collaborative research project NanoChOp (Chemical and optical characterisation of nanomaterials in biological systems), in casu suspensions of silica nanoparticles and CdSe/CdS/ZnS quantum dots. This paper is the first to illustrate how to assess whether nanoparticle test materials meet the requirements of a 'reference material' (ISO Guide 30:2015) or rather those of the recently defined category of 'representative test material' (ISO TS 16195:2013). The NanoChOp test materials were investigated with small-angle X-ray scattering (SAXS), dynamic light scattering (DLS) and centrifugal liquid sedimentation (CLS) to establish whether they complied with the required monomodal particle size distribution. The presence of impurities, aggregates, agglomerates and viable microorganisms in the suspensions was investigated with DLS, CLS, optical and electron microscopy and via plating on nutrient agar. Suitability of surface functionalization was investigated with attenuated total reflection Fourier transform infrared spectrometry (ATR-FTIR) and via the capacity of the nanoparticles to be fluorescently labeled or to bind antibodies. Between-unit homogeneity and stability were investigated in terms of particle size and zeta potential. This paper shows that only based on the outcome of a detailed characterization process one can raise the status of a test material to representative test material or reference material, and how this status depends on its intended use.
| Reference Key |
eroebben2015frontiersreference
Use this key to autocite in the manuscript while using
SciMatic Manuscript Manager or Thesis Manager
|
|---|---|
| Authors | ;Gert eRoebben;Vikram eKestens;Zoltan eVarga;Jean eCharoud-Got;Yannic eRamaye;Christian eGollwitzer;Dorota eBartczak;Daniel eGeißler;James eNoble;Stéphane eMazoua;Nele eMeeus;Philippe eCorbisier;Marcell ePalmai;Judith eMihály;Michael eKrumrey;Julie eDavies;Ute eResch-Genger;Neelam eKumarswami;Caterina eMinelli;Aneta eSikora;Heidi eGoenaga-Infante |
| Journal | spatium |
| Year | 2015 |
| DOI |
10.3389/fchem.2015.00056
|
| URL | |
| Keywords |
Citations
No citations found. To add a citation, contact the admin at info@scimatic.org
Comments
No comments yet. Be the first to comment on this article.