from Red Mushroom Attenuates Formaldehyde-Induced Liver Damage in Experimental Male Rat Model.

Clicks: 427
ID: 127990
2020
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #6 of 35 articles by views in Biology

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The majority of liver-related illnesses are caused by occupational and domestic exposure to toxic chemicals like formaldehyde (FA), which is widely common in Africa and the world at large. Hence, measures should be taken to protect humans from its hazardous effects. This study, therefore, examines the protective potential of (100 mg/kg body weight) on formaldehyde-induced (40%) liver oxido-inflammation in male rats. Male Wistar rats, 150-200 g, were allotted into four groups of 10 animals as follows: Group 1 was orally treated with 1 mg/mL distilled water, Group 2 was exposed to a 40% formaldehyde vapor environment for 30 min per day, Group 3 was orally treated with 100 mg/kg ethanol extract of , and Group 4 was co-administered formaldehyde and 100 mg/kg ethanol extract of . Rats were then sacrificed 24 h after administering the last dose of treatment, and the livers were excised. significantly reversed the formaldehyde-mediated reduction in body and organ weight. administration significantly prevented oxido-inflammation by reducing the levels of hydrogen peroxide and malondialdehyde and increasing the activity of antioxidant enzymes and glutathione contents, as well as the normal level of nitrite and myeloperoxidase production in FA-treated rats. Additionally, reversed a large decline in proinflammatory markers in formaldehyde. Furthermore, restores formaldehyde-induced histological alterations in the liver. Collectively, our results provide valuable information on the protective potential of in protecting formaldehyde-induced liver oxido-inflammation in male rats.
Reference Key
oluwafemi-adetuyi2020biology Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Oluwafemi Adetuyi, Babatunde;Olamide Okeowo, Tolulope;Adefunke Adetuyi, Oluwatosin;Abraham Adebisi, Oluwaseun;Ogunlana, Olubanke Olujoke;Janet Oretade, Oyeyemi;Marraiki, Najat;Beshbishy, Amany Magdy;N Welson, Nermeen;Batiha, Gaber El-Saber;
Journal Biology
Year 2020
DOI
E313
URL
Keywords
formaldehyde inflammation oxidative stress liver ganoderma lucidum Medicinal Plants Prevention flavonoids phenolic compounds antiviral activity

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.