microtubule

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1
Synthesis and biological evaluation of novel shikonin-benzo[b]furan derivatives as tubulin polymerization inhibitors targeting the colchicine binding site.
Shao, Yu-Ying;Yin, Yong;Lian, Bao-Ping;Leng, Jia-Fu;Xia, Yuan-Zheng;Kong, Ling-Yi;
2020 European journal of medicinal chemistry DOI: S0223-5234(20)30072-... 208 views
2
Primary cilia act as microgravity sensors by depolymerizing microtubules to inhibit osteoblastic differentiation and mineralization.
Shi, Wengui;Zhang, Yanan;Chen, Keming;He, Jinpeng;Feng, Xiu;Wei, Wenjun;Hua, Junrui;Wang, Jufang;
2020 bone DOI: S8756-3282(20)30126-... 241 views
3
NMK-BH2, a novel microtubule-depolymerising bis (indolyl)-hydrazide-hydrazone, induces apoptotic and autophagic cell death in cervical cancer cells by binding to tubulin at colchicine - site.
Das Mukherjee, Dipanwita;Kumar, N Maruthi;Tantak, Mukund P;Datta, Satabdi;Ghosh Dastidar, Debabrata;...
2020 biochimica et biophysica acta molecular cell resea... DOI: S0167-4889(20)30120-... 317 views
4
Reaction of ketone hydrazones with TeCl: isolation and reactions of novel divinyl telluride.
Okuma, Kentaro;Qu, Yuxuan;Suetome, Aoi;Nagahora, Noriyoshi;
2020 Organic & biomolecular chemistry DOI: 10.1039/d0ob00782j 225 views
5
microtubule-mediated nlrp3 inflammasome activation is independent of microtubule-associated innate immune factor gef-h1 in murine macrophages
;Hsuan-Ju Lai;Yi-Hsuan Hsu;Guan-Ying Lee;Hao-Sen Chiang
2020 Intertax DOI: 10.3390/ijms21041302 261 views
6
janus compounds, 5-chloro-n4-methyl-n4-aryl-9h-pyrimido[4,5-b]indole-2,4-diamines, cause both microtubule depolymerizing and stabilizing effects
;Cristina C. Rohena;April L. Risinger;Ravi Kumar Vyas Devambatla;Nicholas F. Dybdal-Hargreaves;Roma...
2016 Journal of ethnopharmacology DOI: 10.3390/molecules211... 163 views
7
centrosome positioning in dictyostelium: moving beyond microtubule tip dynamics
;Michael P. Koonce;Irina Tikhonenko
2018 Frontiers in psychology DOI: 10.3390/cells7040029 165 views
8
a brief history of research on mitotic mechanisms
;J. Richard McIntosh;Thomas Hays
2016 Journal of microencapsulation DOI: 10.3390/biology50400... 183 views

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colchicine binding site shikonin-benzo[b]furan derivatives tubulin polymerization inhibitors osteoblasts microgravity primary cilium apoptosis autophagy mitosis cervical cancer bis (indolyl)-hydrazide-hydrazone macrophage inflammasome nlrp3 inflammationbiology (general)chemistry Cancer colchicine siteorganic chemistry centrosome dynein