Resistance to macrolides in clinical isolates of Streptococcus pyogenes due to ribosomal mutations

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ID: 271185
2002
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Résumé
Mutations at a similar position in ribosomal protein L4 and 23S rRNA have been reported previously in macrolide-resistant pneumococci. This report shows that similar mutations can be found in macrolide-resistant S. pyogenes.
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Auteurs Malbruny B;Nagai K;Coquemont M;Bozdogan B;Andrasevic AT;Hupkova H;Leclercq R;Appelbaum PC;;
Revue The Journal of antimicrobial chemotherapy
Année 2002
DOI
DOI non trouvé
URL
http://www.ncbi.nlm.nih.gov/pubmed/12039885
Mots-clés
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine adult Infant drug resistance sequence homology amino acid anti-bacterial agents / pharmacology* streptococcus pyogenes / isolation & purification streptococcal infections / microbiology streptococcus pyogenes / drug effects* microbial sensitivity tests / methods macrolides streptococcal infections / drug therapy bacterial / genetics* mutation / genetics* streptococcus pyogenes / genetics* pmid:12039885 doi:10.1093/jac/dkf038 brigitte malbruny kensuke nagai peter c appelbaum microbial sensitivity tests / statistics & numerical data ribosomal proteins / genetics*

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