DNA origami cryptography for secure communication.

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ID: 93695
2019
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Abstract
Biomolecular cryptography exploiting specific biomolecular interactions for data encryption represents a unique approach for information security. However, constructing protocols based on biomolecular reactions to guarantee confidentiality, integrity and availability (CIA) of information remains a challenge. Here we develop DNA origami cryptography (DOC) that exploits folding of a M13 viral scaffold into nanometer-scale self-assembled braille-like patterns for secure communication, which can create a key with a size of over 700 bits. The intrinsic nanoscale addressability of DNA origami additionally allows for protein binding-based steganography, which further protects message confidentiality in DOC. The integrity of a transmitted message can be ensured by establishing specific linkages between several DNA origamis carrying parts of the message. The versatility of DOC is further demonstrated by transmitting various data formats including text, musical notes and images, supporting its great potential for meeting the rapidly increasing CIA demands of next-generation cryptography.
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zhang2019dnanature Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhang, Yinan;Wang, Fei;Chao, Jie;Xie, Mo;Liu, Huajie;Pan, Muchen;Kopperger, Enzo;Liu, Xiaoguo;Li, Qian;Shi, Jiye;Wang, Lihua;Hu, Jun;Wang, Lianhui;Simmel, Friedrich C;Fan, Chunhai;
Journal Nature communications
Year 2019
DOI
10.1038/s41467-019-13517-3
URL
Keywords
Wireless sensor networks security iot correlation information leakage probability distribution pseudo-random generator

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