AAV vector-mediated in vivo reprogramming into pluripotency

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ID: 86234
2018
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Abstract
In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses.
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Authors Senís, Elena;Mosteiro, Lluc;Wilkening, Stefan;Wiedtke, Ellen;Nowrouzi, Ali;Afzal, Saira;Fronza, Raffaele;Landerer, Henrik;Abad, Maria;Niopek, Dominik;Schmidt, Manfred;Serrano, Manuel;Grimm, Dirk;
Journal Nature communications
Year 2018
DOI
DOI not found
URL
http://link.springer.com/article/10.1038/s41467-018-05059-x
Keywords
chemistry Biology (General) Medicine (General) Pediatrics Science physics neoplasms. tumors. oncology. including cancer and carcinogens plant culture nuclear and particle physics. atomic energy. radioactivity astrophysics engineering geology. rock mechanics. soil mechanics. underground construction

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