Application of Metabolomics to Renal and Cardiometabolic Diseases.

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ID: 82985
2020
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Ranked #2 of 139 articles by views in methods in molecular biology (clifton, nj)

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Abstract
Metabolomics has been increasingly applied to study renal and related cardiometabolic diseases, including diabetes and cardiovascular diseases. These studies span cross-sectional studies correlating metabolites with specific phenotypes, longitudinal studies to identify metabolite predictors of future disease, and physiologic/interventional studies to probe underlying causal relationships. This chapter provides a description of how metabolomic profiling is being used in these contexts, with an emphasis on study design considerations as a practical guide for investigators who are new to this area. Research in kidney diseases is underlined to illustrate key principles. The chapter concludes by discussing the future potential of metabolomics in the study of renal and cardiometabolic diseases.
Reference Key
rebholz2020applicationmethods Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Rebholz, Casey M;Rhee, Eugene P;
Journal methods in molecular biology (clifton, nj)
Year 2020
DOI
10.1007/978-1-0716-0239-3_20
URL
Keywords
Biomarker cardiovascular disease metabolomics renal disease cardiometabolic disease study design replication

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