Response to "Reply to: 'The decreasing predictive power of MELD in an era of changing etiology of liver disease'".
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2020
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Abstract
We appreciate Kwong et al.'s utilization of Harrell's c-statistic and its ability to incorporate follow-up time as a valuable contribution to the discussion about our group's findings. We acknowledge that the conventional area under receiver-operating-characteristic curve concordance statistic has limitations; however, we selected the conventional c-statistic to remain methodologically consistent with the manner in which the Model for End-Stage Liver Disease (MELD) was originally designed and validated, first to predict post-TIPS survival, then when applied to ESLD generally, and finally when integrated into allocation.
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godfrey2020responseamerican
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| Authors | Godfrey, Elizabeth L;Malik, Tahir H;Lai, Jennifer C;Mindikoglu, Ayse L;Galván, N Thao N;Cotton, Ronald T;O'Mahony, Christine A;Goss, John A;Rana, Abbas; |
| Journal | american journal of transplantation : official journal of the american society of transplantation and the american society of transplant surgeons |
| Year | 2020 |
| DOI |
10.1111/ajt.15783
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