Treating Penile Cancer in the Immunotherapy and Targeted Therapy Era

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ID: 8007
2019
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Abstract
While localized penile cancers are typically treated surgically and metastatic penile cancers benefit from standard chemotherapy, there have been studies on the horizon demonstrating immunotherapy as a novel approach to metastatic penile cancers that have failed standard chemotherapy. We report a case series of two patients who improved on immunotherapy after progressing with standard chemotherapy regimens. The first case describes a 64-year-old male with a penile mass and significant lymphadenopathy who had surgical resection and adjuvant chemotherapy prior to continued disease progression. He was started on anti-EGFR treatment and improved initially, but he eventually had progression of disease. The second case describes a 79-year-old male with a penile mass who was treated with surgical resection and started on adjuvant chemoradiation, but he developed recurrence and nodal involvement. Therefore, second-line therapy of the PD-L1 inhibitor was started in this patient. There were no available clinical trials for penile cancer patients who progressed beyond the standard surgical therapy and chemotherapy.
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gavin2019treatingcase Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Hui, Gavin;Ghafouri, Sanaz N.;Shen, John;Liu, Sandy;Drakaki, Alexandra;Hui, Gavin;Ghafouri, Sanaz N.;Shen, John;Liu, Sandy;Drakaki, Alexandra;
Journal case reports in oncological medicine
Year 2019
DOI
10.1155/2019/8349793
URL
https://www.hindawi.com/journals/crionm/2019/8349793/abs/
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