Multiorgan involvement and management in children with Down Syndrome.

Clicks: 403
ID: 75803
2020
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #13 of 170 articles by views in acta paediatrica (oslo, norway : 1992)

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 170 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
To review multiorgan involvement and management in children with Down Syndrome (DS).A literature review of articles from 1980 to 2019 using the MEDLINE interface of Pubmed was performed using the following search terms- [Down Syndrome] or [Trisomy 21] AND [Cardiology] or [Respiratory] or [neurodevelopment] or [epilepsy] or [musculoskeletal] or [immune system] or [haematological] or [endocrine] or [gastrointestinal] or [ophthalmological] or [Ear Nose Throat] or [dermatology] or [renal].Congenital heart disease particularly septal defects occur in over 60% of infants with DS and 5-34% of infants develop persistent pulmonary hypertension of the newborn irrespective of a diagnosis of congenital heart disease. Early recognition and management of aspiration, obstructive sleep apnoea and recurrent lower respiratory tract infections (LRTI) could reduce risk of developing pulmonary hypertension in later childhood. Children with DS have an increased risk of autistic spectrum disorder, attention deficit disorder and epilepsy particularly infantile spasms which are associated with poor neurodevelopmental outcomes. Congenital anomalies of the gastrointestinal and renal system as well as autoimmune diseases, coeliac disease, arthropathy, thyroid dysfunction fold diabetes mellitus and dermatological conditions are more common. Hearing and visual anomalies are also well recognised association with DS.Children with DS are at an increased risk of multiorgan comorbidities. Organ-specifc health surveillance may provide holistic care for the children and families with DS throughout childhood.
Reference Key
lagan2020multiorganacta Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Lagan, Niamh;Huggard, Dean;Mc Grane, Fiona;Leahy, Timothy Ronan;Franklin, Orla;Roche, Edna;Webb, David;O' Maricaigh, Aengus;Cox, Des;Elkuffash, Afif;Greally, Peter;Balfe, Joanne;Molloy, Eleanor J;
Journal acta paediatrica (oslo, norway : 1992)
Year 2020
DOI
10.1111/apa.15153
URL
Keywords
Screening down syndrome health surveillance guidelines multiorgan involvement trisomy 21

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.