Ligand-Controlled Direct γ-C-H Arylation of Aldehydes.

Clicks: 102
ID: 71664
2019
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #192 of 192 articles by views in angewandte chemie (international ed in english)

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 192 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The first example of Pd(II)-catalyzed γ-C(sp3)-H functionalization of aliphatic and heteroaryl aldehydes was developed using a transient ligand and an external ligand, concurrently. A wide array of γ-arylated aldehydes were readily accessed without pre-installing any internal directing groups. The catalytic mechanism was studied by performing deuterium-labelling experiments which indicated that the γ-C(sp3)-H bond cleavage acts as the rate-limiting step during the reaction process. This reaction could be performed on a gram-scale, and it also showed its potential applications on the design and synthesis of new mechanofluorochromic materials with blue-shifted mechanochromism properties.
Reference Key
ge2019ligandcontrolledangewandte Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ge, Haibo;Li, Bijin;Lawrence, Brianna;Li, Guigen;
Journal angewandte chemie (international ed in english)
Year 2019
DOI
10.1002/anie.201913126
URL
Keywords
c-h functionalization * aldehydes * transient directing group * palladium-catalyzed * mechanochromic materials

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.