Evidence-based approach for managing hypertension in type 2 diabetes

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ID: 6584
2010
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Abstract
Evidence-based approach for managing hypertension in type 2 diabetes Gerti Tashko1, Robert A Gabbay21Division of Endocrinology, Diabetes, and Metabolism, Penn State College of Medicine, Hershey, PA, USA; 2Penn State Institute for Diabetes and Obesity, Penn State College of Medicine, Penn State Milton S Hershey Medical Center, Hershey, PA, USAAbstract: Blood pressure (BP) control is a critical part of managing patients with type 2 diabetes. Perhaps it is the single most important aspect of diabetes care, which unlike hyperglycemia and dyslipidemia can reduce both micro- and macrovascular complications. Hypertension is more prevalent in individuals with diabetes than general population, and in most cases its treatment requires two or more pharmacological agents (about 30% of individuals with diabetes need 3 or more medications to control BP). In this article we describe the key evidence that has contributed to our understanding that reduced BP translates into positive micro- and macrovascular outcomes. We review the data supporting current recommendation for BP target < 130/80 mmHg. Two studies suggest that a lower BP goal could be even more beneficial. We also present the comparative benefits of various antihypertensive drugs in reducing diabetes-related micro- and macrovascular complications. Finally we propose an evidence-based algorithm of how to initiate and titrate antihypertensive pharmacotherapy in affected individuals. Overall, achieving BP < 130/80 mmHg is more important than searching for the “best” antihypertensive agent in patients with diabetes.Keywords: blood pressure control, treatment protocol, fixed dose combination, clinical inertia, adherence
Reference Key
gerti2010evidencebasedintegrated Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gerti Tashko;Robert A Gabbay and
Journal integrated blood pressure control
Year 2010
DOI
10.2147/IBPC.S6984
URL
Keywords Keywords not found

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