Co-production of MCR-1 and NDM-5 in Escherichia coli isolated from a colonization case of inpatient

Clicks: 640
ID: 6117
2018
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Steady

Ranked #7 of 1,693 articles by views in Infection and drug resistance

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 1,693 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Co-production of MCR-1 and NDM-5 in Escherichia coli isolated from a colonization case of inpatient Siyuan Feng,1,2,* Cong Shen,1,2,* Hongtao Chen,3 Xiaobin Zheng,4 Yong Xia,5 Lan-Lan Zhong,1,2 Xi Huang,6 Xinwei Wu,7 Guo-Bao Tian1,2 1Department of Immunology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China; 2Key Laboratory of Tropical Diseases Control, Sun Yat-sen University, Ministry of Education, Guangzhou, China; 3Department of Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China; 4Department of Respiratory Medicine, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China; 5Department of Clinical Laboratory Medicine, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, China; 6Program of Pathobiology and Immunology, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China; 7Department of Microbiology, Guangzhou Center for Disease Control and Prevention, Guangzhou, China *These authors contributed equally to this work Abstract: Colistin is increasingly used as an antibiotic of last resort for treating carbapenem-resistant Enterobacteriaceae. Mobile colistin resistance gene mcr-1 has been increasingly reported in Enterobacteriaceae around the world. Of particular concern is the spread of mcr-1 into carbapenemase-producing Enterobacteriaceae, which results in highly drug-resistant strains that are potentially untreatable. Notably, such mcr-1-carrying isolates harboring carbapenemase genes have been reported in animals and patients with infection. Here, we report an Escherichia coli strain carrying co-transferable mcr-1-harboring IncX4 and blaNDM-5-harboring IncX3 plasmids, which was recovered in the context of fecal colonization. Keywords: Escherichia coli, MCR-1, NDM-5, co-production
Reference Key
siyuan2018coproductioninfection Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Siyuan Feng;Cong Shen;Hongtao Chen;Xiaobin Zheng;Yong Xia;Lan-Lan Zhong;Xi Huang;Xinwei Wu;Guo-Bao Tian and
Journal Infection and drug resistance
Year 2018
DOI
10.2147/IDR.S171164
URL
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.