Epidemiology of and risk factors for infection with extended-spectrum β-lactamase-producing carbapenem-resistant Enterobacteriaceae: results of a double case–control study

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2018
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Abstract
Epidemiology of and risk factors for infection with extended-spectrum beta-lactamase-producing carbapenem-resistant Enterobacteriaceae: results of a double case-control study Xiaolang Tian,* Shan Sun,* Xiaojiong Jia,* Hua Zou, Shuang Li, Liping Zhang Department of Laboratory Medicine, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, People’s Republic of China *These authors contributed equally to this work Purpose: Carbapenem-resistant Enterobacteriaceae (CRE) have been increasingly reported worldwide and pose a serious public threat, but the clinical significance of extended-spectrum β-lactamase (ESBL) production in CRE is not well established. Patients and methods: A retrospective case–case–control study was conducted to identify the clinical characteristics of patients with ESBL-CRE. The susceptibility of isolates obtained from these patients was assessed. The detection of ESBL and carbapenemase-related genes was performed by PCR methods. Predictors of 30-day mortality in patients with ESBL-CRE infection were also identified in our study. Results: A total of 149 patients with CRE infection caused by Enterobacter cloacae (n
Reference Key
xiaolang2018epidemiologyinfection Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Xiaolang Tian;Shan Sun;Xiaojiong Jia;Hua Zou;Shuang Li;Liping Zhang and
Journal Infection and drug resistance
Year 2018
DOI
10.2147/IDR.S173456
URL
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