A LysM effector subverts chitin-triggered immunity to facilitate arbuscular mycorrhizal symbiosis.

Clicks: 423
ID: 59223
2019
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #7 of 393 articles by views in The New phytologist

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 393 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Arbuscular mycorrhizal (AM) fungi greatly improve mineral uptake by host plants in nutrient-depleted soil and can intracellularly colonize root cortex cells in the vast majority of higher plants. However, AM fungi possess common fungal cell wall components such as chitin which can be recognized by plant chitin receptors to trigger immune responses, raising the question how AM fungi effectively evade chitin-triggered immune responses during symbiosis. In this study, we characterize a secreted LysM (Lysin motif) effector identified from the model AM fungal species Rhizophagus irregularis, called RiSLM. RiSLM is one of the highest expressed effector proteins in intraradical mycelium during the symbiosis. In vitro binding assays show that RiSLM binds chitin-oligosaccharides and can protect fungal cell walls from chitinases. Moreover, RiSLM efficiently interferes with chitin-triggered immune responses, such as defence gene induction and reactive oxygen species production in Medicago truncatula. Although RiSLM also binds to symbiotic (lipo-)chitooligosaccharides it does not interfere significantly with symbiotic signalling in Medicago. Host-induced gene silencing of RiSLM greatly reduces fungal colonization levels. Taken together, our results reveal a key role for AM fungal LysM effectors to subvert chitin-triggered immunity in symbiosis, pointing to a common role for LysM effectors in both symbiotic and pathogenic fungi.
Reference Key
zeng2019athe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zeng, Tian;Rodriguez-Moreno, Luis;Mansurkhodzaev, Artem;Wang, Peng;van den Berg, Willy;Gasciolli, Virginie;Cottaz, Sylvain;Fort, Sébastien;Thomma, Bart P H J;Bono, Jean-Jacques;Bisseling, Ton;Limpens, Erik;
Journal The New phytologist
Year 2019
DOI
10.1111/nph.16245
URL
Keywords
symbiosis chitin arbuscular mycorrhiza lysm effector plant immunity

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.