Medicinal Importance of Azo and Hippuric Acid Derivatives.

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ID: 58007
2019
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Ranked #7 of 22 articles by views in mini reviews in medicinal chemistry

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Abstract
In this review, specific therapeutic and medicinal advantages including antiviral, antibacterial, antifungal and antitumor, strategies for drug designing, structure-activity relationship, advances in the syntheses of azo and hippuric acid derivatives of more than 50 compounds have been discussed since 2009-2018. It is found that phenyl-diazenyl azo derivatives and pyridinyl substituted hippuric acid derivatives showed promising antiretroviral potential. The incorporation of azo functionality to the respective quinolones and coumarin moieties and the insertion of thiocarbazone to hippuric acid displayed immense antibacterial activities. While, azo and hippuric acid derivatives of triazole and phenyl species gave maximum fungicidal as well as cytotoxic activities.
Reference Key
tahir2019medicinalmini Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tahir, Tehreem;Ashfaq, Muhammad;Asghar, Humna;Shahzad, Mirza I;Tabassum, Rukhsana;Ashfaq, Areeba;
Journal mini reviews in medicinal chemistry
Year 2019
DOI
10.2174/1389557518666180727162018
URL
Keywords
azo dyes drug targets anti-microbial agents antiviral drugs hippuric acid derivatives synthetic chemistry.

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