Identification of novel in vitro antibacterial action of cloprostenol and evaluation of other non-antibiotics against multi-drug resistant A. baumannii.

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ID: 57731
2019
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Abstract
A total of 24 non-antibiotic compounds were tested for their antimicrobial activity against Escherichia coli, Klebsiella pneumoniae (ATCC) and an MDR strain of Acinetobacter baumannii using an agar well diffusion assay. To study additive effects, 100 µl of each antibiotic and 50 µl of each non-antibiotic were used. Cloprostenol was the only non-antibiotic that showed antibacterial activity against all bacterial strains. Cloprostenol had an additive antimicrobial effect with the tested antibiotics against the MDR A. baumannii strain.
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shahzad2019identificationthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Shahzad, Shakeel;Willcox, Mark;Shahzad, Aqeel;
Journal the journal of antibiotics
Year 2019
DOI
10.1038/s41429-019-0244-2
URL
Keywords
TNF-α inflammation viral load nfκb antibodies il-1β hhv-8 il-12

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