Discrete SeNPs-Macromolecule Binding Manipulated by Hydrophilic Interaction.

Clicks: 280
ID: 54141
2018
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #114 of 200 articles by views in International journal of biological macromolecules

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 200 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Nanoparticle-protein conjugates are promising probes for biological diagnostics and versatile building blocks for nanotechnology. Here we demonstrate the interaction of SeNPs with BSA macromolecule simply by physical adsorption method. The interaction between SeNPs and BSA has been investigated by UV-Vis, fluorescence, circular dichroism (CD) spectroscopic and thermal methods. The esterase-like activity of BSA towards PNPA was investigated in the presence of SeNPs. The effects of SeNPs on the stability and conformational changes of BSA were studied, which indicated that the binding of SeNPs with BSA induced relative changes in secondary structure of protein. SeNPs acted as a structure stabilizer for BSA which was further confirmed by thermal denaturation study. The hydrophilic bonding forces played important roles in the BSA-SeNPs complex formation. The putative binding site of SeNPs on BSA was near to Sudlow's site II. The hydrophilic interaction of SeNPs on the stability and structure of BSA would find promising application in drug delivery system.
Reference Key
pansare2018discreteinternational Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Pansare, Amol V;Shedge, Amol A;Patil, Vishwanath R;
Journal International journal of biological macromolecules
Year 2018
DOI
S0141-8130(17)30370-7
URL
Keywords
bsa esterase-like activity senps

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.