Prevalence of diabetes, pre-diabetes and associated risk factors: second National Diabetes Survey of Pakistan (NDSP), 2016-2017.

Prevalensi diabetes, pradiabetes, dan faktor risiko terkait: Survei Diabetes Nasional Pakistan (NDSP) kedua, 2016–2017.

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ID: 47197
2018
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Abstract
The second National Diabetes Survey of Pakistan (second NDSP) was planned to ascertain the updated prevalence of diabetes, pre-diabetes and associated risk factors at the national and provincial levels.The survey was conducted by using multistage clustering technique in all four provinces of Pakistan from February 2016 to August 2017. An estimated sample size of 10 800 was calculated using probability sampling and multistage stratified sampling technique. Twenty-seven clusters were selected out of total 213 clusters from all four provinces (strata) of Pakistan. A total of 46 subclusters were selected by using the 'Rule of thumb'. Out of 12 486 targeted individuals, 10 834 study subjects finally participated in the study (87% response rate). Seventeen trained teams collected data using the structured questionnaire. The clinical and anthropometric measurements included height, weight, blood pressure, waist circumference and waist-to-hip ratio while the blood tests included Oral Glucose Tolerance Test (OGTT), haemoglobin A1c and fasting lipid profiles. WHO criteria were used for the diagnosis of diabetes and pre-diabetes.Overall weighted prevalence of diabetes was 26.3%, of which 19.2% had known diabetes, and 7.1% were newly diagnosed people with diabetes. Prevalence of diabetes in urban and rural areas was 28.3% and 25.3%, respectively. Prevalence of pre-diabetes was 14.4% (15.5% in urban areas and 13.9% in rural areas). Age greater than or equal to 43 years, family history of diabetes, hypertension, obesity and dyslipidaemia were significant associated risk factors for diabetes.The findings of the 2nd NDSP imply that diabetes has reached epidemic proportion and urgently need national strategies for early diagnosis and effective management as well as cost-effective diabetes primary prevention programme in Pakistan.
Survei Diabetes Nasional Pakistan kedua (NDSP kedua) dirancang untuk memastikan prevalensi terkini dari diabetes, pradiabetes, dan faktor-faktor risiko terkait pada tingkat nasional dan provinsi. Survei ini dilakukan dengan menggunakan teknik klaster bertingkat di keempat provinsi Pakistan dari Februari 2016 hingga Agustus 2017. Perkiraan ukuran sampel sebesar 10.800 dihitung menggunakan teknik pengambilan sampel probabilitas dan pengambilan sampel bertingkat terstratifikasi. Dua puluh tujuh klaster dipilih dari total 213 klaster dari seluruh empat provinsi (strata) di Pakistan. Sebanyak 46 subklaster dipilih dengan menggunakan 'rule of thumb'. Dari 12.486 individu yang ditargetkan, 10.834 subjek penelitian akhirnya berpartisipasi dalam studi ini (tingkat respons 87%). Tujuh belas tim terlatih mengumpulkan data menggunakan kuesioner terstruktur. Pengukuran klinis dan antropometri mencakup tinggi badan, berat badan, tekanan darah, lingkar pinggang, dan rasio lingkar pinggang-pinggul, sedangkan pemeriksaan darah mencakup Tes Toleransi Glukosa Oral (TTGO), hemoglobin A1c, dan profil lipid puasa. Kriteria WHO digunakan untuk penegakan diagnosis diabetes dan pradiabetes. Prevalensi tertimbang keseluruhan untuk diabetes adalah 26,3%, dengan 19,2% telah terdiagnosis diabetes sebelumnya, dan 7,1% merupakan penyandang diabetes yang baru terdiagnosis. Prevalensi diabetes di wilayah perkotaan dan perdesaan masing-masing adalah 28,3% dan 25,3%. Prevalensi pradiabetes adalah 14,4% (15,5% di wilayah perkotaan dan 13,9% di wilayah perdesaan). Usia lebih dari atau sama dengan 43 tahun, riwayat keluarga dengan diabetes, hipertensi, obesitas, dan dislipidemia merupakan faktor risiko signifikan yang berkaitan dengan diabetes. Temuan NDSP ke-2 ini mengindikasikan bahwa diabetes telah mencapai proporsi epidemi dan sangat membutuhkan strategi nasional untuk diagnosis dini dan penatalaksanaan yang efektif, serta program pencegahan primer diabetes yang hemat biaya di Pakistan.
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Authors Basit, Abdul;Fawwad, Asher;Qureshi, Huma;Shera, A S;, ;
Journal BMJ open
Year 2018
DOI
10.1136/bmjopen-2017-020961
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