Neuroprotective carbazole alkaloids from the stems and leaves of .

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ID: 45818
2019
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Abstract
The investigation on the stems and leaves of led to the isolation of a previously undescribed carbazole alkaloid, clausenalenine A (), along with seven known analogues (-). The structure of was elucidated based on comprehensive spectroscopic analyses and the known compounds were identified by comparisons with data reported in the literatures. All known compounds (-) were isolated from for the first time. All isolated compounds were evaluated for their neuroprotective activities against 6-hydroxydopamine induced cell death in human neuroblastoma SH-SY5Y cells . Compounds - showed significant neuroprotective effects with EC values ranging from 0.68 to 18.76 μM.
Reference Key
yan2019neuroprotectivenatural Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yan, Gui;Li, Yu-Jie;Zhao, Ying-Ying;Guo, Jia-Ming;Zhang, Wen-Hao;Zhang, Ming-Ming;Fu, Yan-Hui;Liu, Yan-Ping;
Journal Natural product research
Year 2019
DOI
10.1080/14786419.2019.1652285
URL
Keywords
clausena lenis carbazole alkaloid clausenalenine a neuroprotective activities

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