Sesquiterpenoids from .
Clicks: 172
ID: 40271
2019
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Abstract
Sixteen sesquiterpenoids (-), including two new compounds namely saussucostusosides A and B ( and ), were isolated from the roots of by various chromatographic separations. Their structures were elucidated by 1 D and 2 D NMR and HR-QTOF-MS experiments. Among isolated compounds, costunlide (), 3-[4-hydroxymethacryloyloxy]-8-hydroxycostunolide () and 11,13-dihydrozaluzanin C () exhibited potent inhibitory effects on LPS-induced NO production in RAW264.7 cells with IC values of 7.08 ± 0.34, 2.40 ± 0.06 and 5.55 ± 0.24 µM, respectively.
| Reference Key |
hanh2019sesquiterpenoidsnatural
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|---|---|
| Authors | Hanh, Tran Thi Hong;Cham, Pham Thi;My, Nguyen Thi Thuy;Cuong, Nguyen The;Dang, Nguyen Hai;Quang, Tran Hong;Huong, Tran Thu;Cuong, Nguyen Xuan;Nam, Nguyen Hoai;Minh, Chau Van; |
| Journal | Natural product research |
| Year | 2019 |
| DOI |
10.1080/14786419.2019.1650357
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| URL | |
| Keywords | Keywords not found |
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