Mapping and Outcome Implications of Left Atrial Low Voltage Regions as Determined by a Novel 122-electrode Spherical Mapping and Ablation Catheter

Clicks: 23
ID: 339222
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #130 of 141 articles by views in EP Europace

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 141 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Aims A novel 122-electrode spherical mapping/pulsed field ablation (PFA) device is known to effectively ablate atrial fibrillation (AF). The aim of this study is threshold optimization of LVA for the unique geometry of the Globe electrodes and the prognostic association, to evaluate if the extent of low voltage areas could predict recurrence. Methods and Results The PULSAR study was an IDE trial of 183 patients undergoing first-time paroxysmal AF ablation with one-year outcomes of any atrial arrhythmia. During this study, a subset of patients (n=82) had detailed pre-ablation voltage maps performed with the catheter. Pulmonary vein isolation (PVI) was then performed with PFA. Patients were followed with weekly transtelephonic monitoring, ECG, and Holters at 3, 6, and 12 months. Recurrence was defined as any atrial arrhythmia (AA) > 30 seconds. Receiver operator curve (ROC) analysis revealed that a low voltage threshold of 1.0 mV had the highest value (0.735). The percentage LVA surface area resulting from a threshold of 1.0 mV that predicted AA recurrence was 11.6%. Univariate and multivariate analysis revealed the percentage LVA was the strongest predictor of AA recurrence. The 12-month freedom from AA was 84.6% and 52.9% for subjects under and over the low voltage area threshold respectively. Conclusions A voltage threshold of 1.0 mV is proposed as a threshold for defining LVA using the spherical catheter, but a range of approximately 0.5-1.5 mV yielded similar performance. Increased low voltage area in the pre-ablation atrial map was associated with a higher risk of AA recurrence.
Reference Key
openalex_W7225464794 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Atul Verma, Hans Kottkamp, Hugh G Calkins, Devi G. Nair, Philipp Sommer, Ayman Ali Hussein, Burghard Schumacher, Srinivas Rao Dukkipati, Petr Neužil, Saumil R. Oza, Christopher E. Woods, Marc William Deyell, José Osorio, Vivek Yerrapu Reddy
Are you one of these authors? Claim your profile
Journal EP Europace
Year 2026
DOI
10.1093/europace/euag315
URL
https://academic.oup.com/europace/advance-article-pdf/doi/10.1093/europace/euag315/73268271/euag315.pdf
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.