Precordial Swirl Sign: A Subtle ECG Clue Unmasking Anterior Myocardial Ischemia

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ID: 333817
2026
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Abstract
Precordial swirl sign may provide a clue to anterior myocardial ischemia in patients whose electrocardiograms do not meet conventional ST-segment elevation myocardial infarction criteria. A 75-year-old man with previous coronary stenting presented with worsening chest pain and an initially negative troponin result. His admission electrocardiogram showed focal ST-segment elevation in V1, a hyperacute T wave in V2, and reciprocal ST-segment depression in V5-V6. Subsequent anterior Twave inversion and troponin elevation supported an ischemic interpretation. Coronary angiography revealed approximately 90% proximal left anterior descending coronary artery in-stent restenosis with TIMI 2 flow. Balloon angioplasty followed by drug-coated balloon treatment restored TIMI 3 flow. This case illustrates the importance of interpreting opposing precordial ST-T changes in relation to the ischemic vector rather than considering ST-segment elevation thresholds alone. Recognition of this pattern may prompt serial electrocardiography, repeat biomarker testing, and timely assessment for coronary intervention.
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Authors Myoung-Joon Lee, Mingjie Zhong, Yun-Tao Zhao
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Journal qjm : monthly journal of the association of physicians
Year 2026
DOI
10.1093/qjmed/hcag302
URL
https://academic.oup.com/qjmed/advance-article-pdf/doi/10.1093/qjmed/hcag302/72452760/hcag302.pdf
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