Community-Acquired Infection Caused by mcr-1 and bla OXA-48-Producing Escherichia coli : A Case Highlighting Limitations of Selective Susceptibility Testing

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ID: 333370
2026
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Ranked #231 of 241 articles by views in FEMS microbiology letters

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Abstract
Abstract Selective antimicrobial susceptibility supports antimicrobial stewardship strategy but may have limitations in high-resistance prevalence settings. We report a community-acquired infection of necrotic metastatic inguinal lymphadenopathy caused by two mcr-producing Escherichia coli isolates, including one blaOXA-48 producer. Initial selective susceptibility testing delayed recognition of clinically relevant resistance. This case highlights the risk of silent community dissemination of high-priority resistance determinants. It underscores the need for context-adapted susceptibility reporting to balance antimicrobial stewardship and resistance surveillance.
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openalex_W7223130962 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Basma Mnif, Nizar Kardoun
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Journal FEMS microbiology letters
Year 2026
DOI
10.1093/femsle/fnag128
URL
https://doi.org/10.1093/femsle/fnag128
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