Twenty-Eight-Day Pain Trajectories After Standardized Three-Position Coccygeal Infiltration: A Prospective Observational Study of 274 Patients

Clicks: 15
ID: 332993
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #72 of 84 articles by views in regional anesthesia and pain medicine

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Objective To characterize daily pain trajectories after standardized three-position coccygeal infiltration and explore differences by clinical and radiographic subgroups. Design Prospective, single-arm observational cohort study. Setting Specialized orthopedic and spine care setting. Subjects Patients had chronic coccygodynia with symptomatic coccygeal instability confirmed clinically and on paired standing and seated lateral radiographs. Of 668 treated patients receiving a diary, 274 returned complete diaries and were analyzed (41.0%); 394 did not return a diary (59.0%). Methods Patients were treated prone without procedural imaging guidance. Through one skin entry, a 23-gauge needle was directed sequentially to the symptomatic mobile segment, coccygeal tip, and immediately lateral to the coccyx. The standard injectate was mepivacaine 1% (5 mL) plus triamcinolone 40 mg. NRS pain was recorded before infiltration (day 0) and daily through post-injection day 27. Responder thresholds were ≥30%, ≥50%, and, supplementarily, ≥2-point improvement. Results Mean NRS was 5.55 at baseline, increased transiently on post-injection days 1 and 2, and was below baseline on day 3. By day 27, mean NRS was 1.99 (paired change, −3.56; 95% CI, −3.90 to − 3.22; P < 0.001; Cohen dz = 1.24); 220 patients (80.3%) achieved ≥30% improvement and 192 (70.1%) achieved ≥50% improvement. Mean pain decreased further from 3.51 in diary week 3 to 2.73 in diary week 4 (change, −0.78; 95% CI, −0.95 to − 0.61; P < 0.001; Cohen dz = 0.55). More than half of day-20 nonresponders achieved responder status by day 27. Conclusions Three-position coccygeal infiltration was followed by substantial pain reduction through day 27, including further improvement during diary week 4. Causal efficacy cannot be established without a comparison group, and responder estimates may not represent the entire treated population because 59.0% did not return diaries.
Reference Key
openalex_W7222983873 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Loreto C. Pulido, Philipp Koehl, Alexander Schuh, Hugo E J Vankelecom
Journal regional anesthesia and pain medicine
Year 2026
DOI
10.1093/pm/pnag142
URL
https://doi.org/10.1093/pm/pnag142
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.