Dual-color Imaging of Cell-Surface and Intracellular Proteins Using Fluorescent Probes for β-lactamase Tag

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ID: 332635
2026
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Ranked #810 of 811 articles by views in phytochemistry letters

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Abstract
Abstract We herein develop a fluorescein-conjugated β-lactamase inhibitor-based probe, FD-DA, with expanded emission color for labeling proteins through β-lactamase tag. FD-DA specifically labeled intracellular target proteins in live cells after hydrolysis of the ester groups. In combination with a red-fluorescent cell-impermeable probe, dual-color imaging of intracellular and cell surface β-lactamase-tagged proteins was achieved via discriminative labeling.
Reference Key
openalex_W7222827176 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Jiatong Li, Rio Furutani, Masafumi Minoshima, Kazuya Kikuchi
Journal phytochemistry letters
Year 2026
DOI
10.1093/chemle/upag201
URL
https://doi.org/10.1093/chemle/upag201
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