COVID-19 and thrombotic risk in patients with active cancer: a matched cohort study

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ID: 332176
2026
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Abstract
Abstract COVID-19 has been associated with an increased thrombotic risk, potentially exacerbated in patients with active cancer. We conducted a retrospective cohort study including 119 cancer patients with COVID-19 and 214 matched pre-pandemic controls. Patients with COVID-19 had poorer performance status and were more frequently treated with palliative intent. After a median follow-up of 32.7 months, overall thrombotic event rates did not differ between groups. However, after adjustment for clinically relevant covariates and accounting for death as a competing event, COVID-19 status and palliative treatment intent remained independently associated with a higher cumulative incidence of thrombotic events. In conclusion, COVID-19 may increase thrombotic risk in patients with cancer and occurs more frequently in patients with poorer clinical status. These findings are exploratory and require confirmation in larger prospective studies.
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openalex_W7221548136 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors J. Doyen, Alexandre Lacour, Renaud Schiappa, Eva Seutin, Amanda Garrido, Tanguy Pace Loscos, Denis Doyen
Journal jnci cancer spectrum
Year 2026
DOI
10.1093/jncics/pkag110
URL
https://doi.org/10.1093/jncics/pkag110
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