Enhanced occupational noise exposure and reduced telomere length with enhanced risk of heart disease: evidence from two populations

Clicks: 13
ID: 331707
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #165 of 192 articles by views in qjm : monthly journal of the association of physicians

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 192 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
BACKGROUND: Occupational noise exposure has been linked to cardiovascular risk, but its associations with emerging lipid-related cardiovascular predictors and the potential role of leukocyte telomere length (LTL) remain unclear. AIM: This study aimed to investigate associations of occupational noise exposure with the atherogenic index of plasma (AIP) and the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR), and to explore the potential involvement of LTL. DESIGN AND METHODS: This cross-sectional study included 765 Chinese workers and 131,214 participants from the UK Biobank. In the occupational cohort, cumulative noise exposure (CNE) was calculated using occupational histories and workplace noise monitoring data. AIP and NHHR were derived from lipid biomarkers, and LTL was measured by qRT-PCR. Generalized linear models, restricted cubic splines, interaction analyses and mediation analyses were performed. RESULTS: CNE was positively and nonlinearly associated with AIP and NHHR (both P for overall < 0.01 and P for nonlinear < 0.01); negatively associated with LTL (P for overall < 0.01 and P for nonlinear = 0.017). LTL was negatively associated with AIP (β: -0.008; 95% CI: -0.015, -0.002) and NHHR (β: -0.056; 95% CI: -0.078, -0.033). LTL explained the associations of noise level and CNE with NHHR, with the proportions of 16.51% and 34.90%, respectively. Similar associations of occupational noise exposure with AIP and LTL were observed in UKB. CONCLUSION: Our study demonstrates positive associations of occupational noise exposure with AIP and NHHR, and suggests that LTL plays an important role in those associations.
Reference Key
openalex_W7220702686 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yanhong Lai, Zhaomin Chen, Haozhe Zhang, Qiyou Tan, Kaiji Lang, Zhang Hong, Shuo Yang, Yuqin Liu, 陳偉宏, Wenzhen Li, Dongming Wang
Are you one of these authors? Claim your profile
Journal qjm : monthly journal of the association of physicians
Year 2026
DOI
10.1093/qjmed/hcag276
URL
https://doi.org/10.1093/qjmed/hcag276
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.