A kinesin motor complex localizes microtubule-severing proteins to direct gravitropism in Physcomitrium patens

Clicks: 18
ID: 331540
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Emerging

Ranked #244 of 380 articles by views in The Plant cell

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 380 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Gravitropism enables plants to adjust growth direction and architecture in response to gravity. The classical Cholodny-Went theory posits that asymmetric auxin redistribution drives differential growth during gravitropism in seed plants, but the nature of the equivalent asymmetric process in moss protonemata is still unclear. Here, through forward genetic screening, we identified GTRD, which encodes a coiled-coil protein whose loss reverses the direction of protonemal gravitropism. We further demonstrated that GTRD forms a complex with the kinesin-14 motor GTRC, and that GTRC drives the minus-end-directed movement of GTRD along microtubules. This GTRC-GTRD complex transports a microtubule anchoring module MSD1-WDR8 that positions katanin. Under gravistimulation, katanin-dependent microtubule severing facilitates the asymmetric formation of a microtubule focus on the upper flank of the tip cell, where it spatially constrains the apical actin cluster. This cytoskeletal reorganization guides the upward growth of the protonemata. Together, the GTRC-GTRD motor complex spatially organizes katanin-mediated microtubule remodeling to establish cytoskeletal polarity, which serves as a key asymmetric cue that directs gravitropic growth in protonemal tip cells.
Reference Key
openalex_W7220425480 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Zhaoguo Deng, Zhiren Chen, Tongda Xu, Haodong Chen
Are you one of these authors? Claim your profile
Journal The Plant cell
Year 2026
DOI
10.1093/plcell/koag307
URL
https://doi.org/10.1093/plcell/koag307
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.