One-step synthesis of C -alkylated tetrazoles via coupling of ethers with C -sulfonylated tetrazole promoted by a photoexcited aryl ketone
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ID: 329151
2026
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Abstract
Abstract A one-step synthesis of C-alkylated tetrazoles was achieved by coupling of ethers with 1-phenyl-5-methylsulfonyl-1H-tetrazole as the introducing tetrazole source in the presence of photoexcited benzophenone as the C(sp3)–H bond-cleaving agent. The present transformation proceeds via generation of an α-oxy carbon radical derived from the starting ether and can be carried out at ambient temperature even in protic solvents such as alcohol and water.
| Reference Key |
openalex_W7213607103
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|---|---|
| Authors | Reika Nakamura, Toshihiro Murafuji, Shin Kamijo |
| Journal | phytochemistry letters |
| Year | 2026 |
| DOI |
10.1093/chemle/upag188
|
| URL | |
| Keywords | Keywords not found |
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