Effectiveness of an eHealth intervention to improve quality of life in long-term breast cancer survivors: a 9-month randomized controlled trial

Clicks: 1
ID: 328959
2026
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal

Ranked #357 of 357 articles by views in JNCI Journal of the National Cancer Institute

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 357 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Abstract Background Quality of life may deteriorate in long-term breast cancer survivors after treatment. Evidence on the long-term effectiveness of eHealth interventions remains limited. This study aimed to evaluate the longer-term effect of CUMACA-M on overall quality of life over a 9-month follow-up period among long-term breast cancer survivors, compared with usual care. Methods A parallel-group randomized clinical trial was conducted in Spain from November 2023 to January 2025. A total of 201 disease-free long-term breast cancer survivors (≥5 years post-diagnosis) were randomly assigned to a 9-month eHealth intervention (n = 102) or usual care (n = 99). Quality of life was assessed using the Quality of Life–Cancer Survivors scale at baseline and 3, 6, and 9 months. Intention-to-treat analyses used mixed linear models and nonparametric tests as appropriate. Results Retention exceeded 90%. Group-by-time interactions were significant for overall quality of life (P=.006) and psychological well-being (P= .034). Quality of life declined in the control group from 5.83 at baseline to 5.57 at 9 months (change=-0.26, 95% CI=-0.46 to -0.07) but remained stable in the intervention group (5.70 to 5.69). At 9 months, adjusted quality of life favored CUMACA-M (mean difference=0.24, 95% CI = 0.03 to 0.44; P=.024; Cohen d = 0.32). Small significant effects also favored CUMACA-M for physical (P<.001, r = 0.28), social (P=.004, r = 0.23), and psychological well-being (P=.034, Cohen d = 0.40), but not spiritual well-being. Conclusions The eHealth intervention prevented deterioration in quality of life over 9 months among long-term breast cancer survivors. Digital interventions may provide a scalable strategy to support survivorship care. Registration ClinicalTrials.gov NCT05322460; https://clinicaltrials.gov/study/NCT05322460.
Reference Key
openalex_W7140299472 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gustavo Adolfo Pimentel-Parra, Paula Escalada-Hernández, Leticia San Martín‐Rodríguez, Cristina Garcia-Vivar, Nelia Soto-Ruiz
Journal JNCI Journal of the National Cancer Institute
Year 2026
DOI
10.1093/jnci/djag328
URL
https://doi.org/10.1093/jnci/djag328
Keywords Keywords not found

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.