Vision-related quality of life in glaucoma and age-related macular degeneration patients from a middle-income country

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ID: 328057
2026
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Abstract
Abstract Background Vision-related quality of life (VRQoL)—vision’s impact on one’s social, emotional and economic well-being—has not been extensively studied in patients living in middle-income countries. The aim of this study was to compare the VRQoL among age-related macular degeneration (AMD), primary open-angle glaucoma (POAG) and normal subjects in Brazil. Methods This was a case–control, cross-sectional study. Patients with AMD or POAG and normal controls underwent a complete eye examination; all participants answered the Brazilian-Portuguese version of the Visual Function Questionnaire 25 (VFQ-25). Each item was scored and an overall composite score was calculated and compared among groups with an analysis of variance test. Results The sample included 60 patients with AMD, 64 with POAG and 60 controls. All groups were matched for age, gender, ethnic distribution and comorbidities. The VFQ-25 total score was lower in both AMD (50.6±20.9) and POAG (61.8±20.4) as compared with controls (89.2±9.1, p<0.001); scores for AMD patients were lower than for POAG patients (p<0.001). Conclusions Brazilian patients with POAG, and especially AMD, presented significantly lower VRQoL scores, underscoring the need to improve the care of patients with visual impairment in Brazil.
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Authors Renato Maia Macchione, Patrícia Asperti Ottaiano-Poli, Caroline Schiave Germano-Morrel, Kenzo Saito Tomishige, Niro Kasahara
Journal bmc international health and human rights
Year 2026
DOI
10.1093/inthealth/ihag089
URL
https://doi.org/10.1093/inthealth/ihag089
Keywords Keywords not found

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