Implementation of an automated robotic syringe-filling device in a hospital-based sterile products cleanroom

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ID: 326691
2026
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Ranked #134 of 151 articles by views in American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

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Abstract
PURPOSE: To describe the implementation of an automated robotic syringe-filling device within a hospital-based sterile products cleanroom. SUMMARY: Automated intravenous (IV) compounding can reduce compounded product variability, decrease human error, and improve patient and staff safety outcomes. An automated robotic syringe-filling device was implemented to automate sterile syringe preparation. Staff training, workflow redesign, and batching optimization were required for effective implementation. Syringe preparation volume increased from 5,290 syringes in the first month to an average of 22,640 syringes per month by the end of the first year following implementation. Staffing needs decreased from approximately 2.5 full-time equivalents (FTEs) dedicated to manual syringe and automated bagged preparation compounding to 1.7 FTEs for combined staffing of both robots. This labor shift enabled reallocation of technician time to other high-priority tasks. Continuous process improvements increased syringe production efficiency while maintaining similar labor demands. CONCLUSION: Robotic syringe filling significantly improved operational efficiency and capacity while reducing staff dedicated to syringe compounding. Successful implementation required thorough planning, education, and continuous improvement. As system optimization progressed, throughput gains and labor savings were realized, demonstrating the value of automation in a high-volume sterile compounding environment.
Reference Key
openalex_W7204444146 Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Trevor Rice, Alexsandra Nilges, Lindsey Amerine, Angela Yaniv
Journal American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
Year 2026
DOI
10.1093/ajhp/zxag255
URL
https://doi.org/10.1093/ajhp/zxag255
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