P1.177. Supracarinal Lymph Nodal Dissection in Esophageal Squamous Cell Carcinoma Following Neoadjuvant Therapy

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ID: 326201
2026
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Ranked #432 of 453 articles by views in diseases of the esophagus : official journal of the international society for diseases of the esophagus

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Abstract
Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Accurate mediastinal staging remains pivotal to the management of esophageal carcinoma. While subcarinal and perigastric nodal basins are routinely evaluated, the prognostic and staging implications of supracarinal nodal involvement are less clearly defined. This study evaluates the incidence of metastasis to these stations in a contemporary esophagectomy cohort. Methods An audit of a prospective database of esophagogastric cancers was conducted on 64 consecutive patients undergoing esophagectomy with total mediastinal lymphadenectomy for carcinoma esophagus. The data was analysed to determine nodal yield, anatomical distribution of nodal metastasis, and final pathological staging. The frequency and clinical associations of supracarinal nodal involvement were analyzed. Results Pathological nodal metastasis was identified in 18 patients (28.1%). 106 tbL nodal involvement occurred in 2 patients (3.1% overall; 11.1% of node-positive cases) and was uniformly associated with advanced nodal stage (N2/N3) and multi-station mediastinal disease. Tracheobronchial(106tbR) nodal metastasis was similarly observed in 2 patients (3.1% overall; 11.1% of node-positive cases), typically in conjunction with subcarinal or other mediastinal nodal involvement. No cases demonstrated isolated 106tbL or 106tbR metastasis. Median nodal harvest exceeded oncologic adequacy thresholds, supporting comprehensive mediastinal clearance. Conclusion Although infrequent, metastasis to 106tbL or 106tbR nodal stations reflects advanced mediastinal dissemination and is associated with higher pathological nodal stage. Systematic dissection of these stations enhances staging accuracy. However, long term follow up is needed to assess oncological outcomes.
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Authors Caleb Harris, Sandeep Ghosh, Vikas Jagtap, Biswajit Dey, Nari Lyngdoh
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Journal diseases of the esophagus : official journal of the international society for diseases of the esophagus
Year 2026
DOI
10.1093/dote/doag077.325
URL
https://doi.org/10.1093/dote/doag077.325
Keywords Keywords not found

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